ELOC

ELOC
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1LM8, 1LQB, 1VCB, 2C9W, 2IZV, 2MA9, 3DCG, 3ZKJ, 3ZNG, 3ZRC, 3ZRF, 3ZTC, 3ZTD, 3ZUN, 4AJY, 4AWJ, 4B95, 4B9K, 4BKS, 4BKT, 4N9F, 4W9C, 4W9D, 4W9E, 4W9F, 4W9G, 4W9H, 4W9I, 4W9J, 4W9K, 4W9L, 4WQO, 5BO4
Dynodwyr
Cyfenwau	ELOC, SIII, eloC, TCEB1, transcription elongation factor B subunit 1, elongin C
Dynodwyr allanol	OMIM: 600788 HomoloGene: 38083 GeneCards: ELOC
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • GO:0050372 ubiquitin-protein transferase activity Cydrannau o'r gell • cytosol • cnewyllyn cell • elongin complex • nucleoplasm Prosesau biolegol • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • transcription elongation from RNA polymerase II promoter • GO:0009373 regulation of transcription, DNA-templated • transcription by RNA polymerase II • ubiquitin-dependent protein catabolic process • transcription, DNA-templated • regulation of transcription from RNA polymerase II promoter in response to hypoxia • GO:0022415 viral process • positive regulation of transcription elongation from RNA polymerase II promoter • post-translational protein modification • protein ubiquitination Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6921	n/a
Ensembl	ENSG00000154582	n/a
UniProt	Q15369	n/a
RefSeq (mRNA)	NM_001204857 NM_001204858 NM_001204859 NM_001204860 NM_001204861 NM_001204862 NM_001204863 NM_001204864 NM_005648	n/a
RefSeq (protein)	NP_001191786 NP_001191787 NP_001191788 NP_001191789 NP_001191790 NP_001191791 NP_001191792 NP_001191793 NP_005639	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ELOC yw ELOC a elwir hefyd yn Elongin C (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 8, band 8q21.11.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ELOC.

• SIII
• TCEB1

Llyfryddiaeth

• "Indolizine derivatives as HIV-1 VIF-ElonginC interaction inhibitors. ". Chem Biol Drug Des. 2013. PMID 23405965.
• "Design, synthesis and biological evaluation of indolizine derivatives as HIV-1 VIF-ElonginC interaction inhibitors. ". Mol Divers. 2013. PMID 23378232.
• "TCEB1-mutated renal cell carcinoma: a distinct genomic and morphological subtype. ". Mod Pathol. 2015. PMID 25676555.
• "Amplification and overexpression of Elongin C gene discovered in prostate cancer by cDNA microarrays. ". Lab Invest. 2002. PMID 12004003.
• "A human cDNA encoding the small subunit of RNA polymerase II transcription factor SIII.". Gene. 1994. PMID 7821821.