EDA

EDA
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1RJ7, 1RJ8
Dynodwyr
Cyfenwau	EDA, ECTD1, ED1, ED1-A1, ED1-A2, EDA-A1, EDA-A2, EDA1, EDA2, HED, HED1, ODT1, STHAGX1, XHED, XLHED, TNLG7C, ectodysplasin A
Dynodwyr allanol	OMIM: 300451 GeneCards: EDA
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • tumor necrosis factor receptor binding • signaling receptor binding • death receptor agonist activity • death receptor binding Cydrannau o'r gell • integral component of membrane • collagen • endoplasmic reticulum membrane • bilen • Cellbilen • apical part of cell • integral component of plasma membrane • extracellular region • Cytosgerbwd • lipid droplet • intracellular membrane-bounded organelle Prosesau biolegol • trachea gland development • hair follicle placode formation • hair follicle development • cell differentiation • gene expression • positive regulation of canonical Wnt signaling pathway • salivary gland cavitation • tumor necrosis factor-mediated signaling pathway • multicellular organism development • GO:1901313 positive regulation of gene expression • positive regulation of NF-kappaB transcription factor activity • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • positive regulation of I-kappaB kinase/NF-kappaB signaling • pigmentation • cell-matrix adhesion • skin development • cytokine-mediated signaling pathway • regulation of NIK/NF-kappaB signaling • odontogenesis of dentin-containing tooth • regulation of signaling receptor activity • positive regulation of NIK/NF-kappaB signaling Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1896	n/a
Ensembl	ENSG00000158813	n/a
UniProt	Q92838	n/a
RefSeq (mRNA)	NM_001005609 NM_001005610 NM_001005611 NM_001005612 NM_001005613 NM_001005614 NM_001399	n/a
RefSeq (protein)	NP_001005609 NP_001005610 NP_001005612 NP_001005613 NP_001390	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn EDA yw EDA a elwir hefyd yn Ectodysplasin A ac Ectodysplasin-a (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom X dynol, band Xq13.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn EDA.

• ED1
• HED
• EDA1
• EDA2
• HED1
• ODT1
• XHED
• ECTD1
• XLHED
• ED1-A1
• ED1-A2
• EDA-A1
• EDA-A2
• TNLG7C
• STHAGX1

Llyfryddiaeth

• "De novo EDA mutations: Variable expression in two Egyptian families. ". Arch Oral Biol. 2016. PMID 27054699.
• "Novel missense mutation in the EDA gene in a family affected by oligodontia. ". J Orofac Orthop. 2016. PMID 26753551.
• "Identification of a novel mutation of the EDA gene in X-linked hypohidrotic ectodermal dysplasia. ". Genet Mol Res. 2015. PMID 26634545.
• "Novel EDA mutation in X-linked hypohidrotic ectodermal dysplasia and genotype-phenotype correlation. ". Oral Dis. 2015. PMID 26411740.
• "A novel missense mutation in collagenous domain of EDA gene in a Chinese family with X-linked hypohidrotic ectodermal dysplasia.". J Genet. 2015. PMID 25846883.