E2F5

E2F5
Dynodwyr
Cyfenwau	E2F5, E2F-5, E2F transcription factor 5
Dynodwyr allanol	OMIM: 600967 HomoloGene: 1472 GeneCards: E2F5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • DNA binding • transcription factor binding • GO:0001948, GO:0016582 protein binding • protein dimerization activity • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • sequence-specific DNA binding Cydrannau o'r gell • cytoplasm • nucleolus • cnewyllyn cell • transcription regulator complex • nucleoplasm • fibrillar center • RNA polymerase II transcription regulator complex Prosesau biolegol • animal organ morphogenesis • regulation of cell cycle • cell projection organization • GO:0009373 regulation of transcription, DNA-templated • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • transcription, DNA-templated • GO:1901227 negative regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1875	n/a
Ensembl	ENSG00000133740	n/a
UniProt	Q15329	n/a
RefSeq (mRNA)	NM_001083588 NM_001083589 NM_001951	n/a
RefSeq (protein)	NP_001077057 NP_001077058 NP_001942	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn E2F5 yw E2F5 a elwir hefyd yn Transcription factor E2F5 ac E2F transcription factor 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 8, band 8q21.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn E2F5.

• E2F-5

Llyfryddiaeth

• "E2F5 as an independent prognostic factor in esophageal squamous cell carcinoma. ". Anticancer Res. 2013. PMID 24324077.
• "Analysis of genetic aberrations on chromosomal region 8q21-24 identifies E2F5 as an oncogene with copy number gain in prostate cancer. ". Med Oncol. 2013. PMID 23377984.
• "A potential oncogenic role of the commonly observed E2F5 overexpression in hepatocellular carcinoma. ". World J Gastroenterol. 2011. PMID 21274376.
• "E2F5 status significantly improves malignancy diagnosis of epithelial ovarian cancer. ". BMC Cancer. 2010. PMID 20181230.
• "Overexpression of E2F-5 correlates with a pathological basal phenotype and a worse clinical outcome.". Br J Cancer. 2009. PMID 19259095.