DYNLL2

DYNLL2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2XQQ, 3P8M, 4D07, 1PWJ
Dynodwyr
Cyfenwau	DYNLL2, DNCL1B, Dlc2, RSPH22, dynein light chain LC8-type 2
Dynodwyr allanol	OMIM: 608942 HomoloGene: 115597 GeneCards: DYNLL2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • cytoskeletal motor activity • GO:0001948, GO:0016582 protein binding • plus-end-directed microtubule motor activity • dynein intermediate chain binding • dynein light intermediate chain binding • cytoskeletal protein binding • protein homodimerization activity • protein heterodimerization activity • scaffold protein binding Cydrannau o'r gell • cytoplasm • cytosol • cnewyllyn cell • bilen • ciliary tip • centrosome • microtubule • Cellbilen • microtubule associated complex • dynein complex • Cytosgerbwd • mitocondria • cilium • myosin V complex • cytoplasmic dynein complex • myosin complex • GO:0097483, GO:0097481 postsynaptic density • postsynapse • glutamatergic synapse Prosesau biolegol • microtubule-based process • antigen processing and presentation of exogenous peptide antigen via MHC class II • endoplasmic reticulum to Golgi vesicle-mediated transport • positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway • macroautophagy • intraciliary transport involved in cilium assembly • transport along microtubule • cilium assembly • sister chromatid cohesion • GO:0015915 transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	140735	n/a
Ensembl	ENSG00000264364	n/a
UniProt	Q96FJ2	n/a
RefSeq (mRNA)	NM_080677	n/a
RefSeq (protein)	NP_542408	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DYNLL2 yw DYNLL2 a elwir hefyd yn Dynein light chain LC8-type 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17q22.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DYNLL2.

• Dlc2
• DNCL1B
• RSPH22

Llyfryddiaeth

• "Gephyrin interacts with Dynein light chains 1 and 2, components of motor protein complexes. ". J Neurosci. 2002. PMID 12097491.
• "The hDLG-associated protein DAP interacts with dynein light chain and neuronal nitric oxide synthase. ". Genes Cells. 2000. PMID 11122378.
• "DYNLL2 dynein light chain binds to an extended linear motif of myosin 5a tail that has structural plasticity. ". Biochemistry. 2014. PMID 25312846.
• "Affinity, avidity, and kinetics of target sequence binding to LC8 dynein light chain isoforms. ". J Biol Chem. 2010. PMID 20889982.
• "JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis.". Proc Natl Acad Sci U S A. 2003. PMID 12591950.