DYNC1I2

DYNC1I2
Dynodwyr
Cyfenwau	DYNC1I2, DNCI2, IC2, DIC74, dynein cytoplasmic 1 intermediate chain 2, NEDMIBA
Dynodwyr allanol	OMIM: 603331 HomoloGene: 133934 GeneCards: DYNC1I2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • microtubule motor activity • GO:0001948, GO:0016582 protein binding • cytoskeletal motor activity • plus-end-directed microtubule motor activity • dynein light chain binding • dynein heavy chain binding Cydrannau o'r gell • fesigl • cytosol • centrosome • dynein complex • Cytosgerbwd • cytoplasm • microtubule • cytoplasmic dynein complex Prosesau biolegol • antigen processing and presentation of exogenous peptide antigen via MHC class II • endoplasmic reticulum to Golgi vesicle-mediated transport • G2/M transition of mitotic cell cycle • GO:0022415 viral process • microtubule-based movement • ciliary basal body-plasma membrane docking • transport along microtubule • regulation of G2/M transition of mitotic cell cycle Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1781	n/a
Ensembl	ENSG00000077380	n/a
UniProt	Q13409	n/a
RefSeq (mRNA)	NM_001271785 NM_001271786 NM_001271787 NM_001271788 NM_001271789 NM_001271790 NM_001378 NM_001320882 NM_001320883 NM_001320884 NM_001378455 NM_001378456	n/a
RefSeq (protein)	NP_001258714 NP_001258715 NP_001258716 NP_001258717 NP_001258718 NP_001258719 NP_001307811 NP_001307812 NP_001307813 NP_001369 NP_001365384 NP_001365385	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DYNC1I2 yw DYNC1I2 a elwir hefyd yn Cytoplasmic dynein 1 intermediate chain 2 a Dynein cytoplasmic 1 intermediate chain 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q31.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DYNC1I2.

• IC2
• DIC74
• DNCI2

Llyfryddiaeth

• "Dynein regulates cell migration depending on substrate rigidity. ". Int J Mol Med. 2012. PMID 22200735.
• "Levels of kinesin light chain and dynein intermediate chain are reduced in the frontal cortex in Alzheimer's disease: implications for axoplasmic transport. ". Acta Neuropathol. 2012. PMID 22094641.
• "Specificity of cytoplasmic dynein subunits in discrete membrane-trafficking steps. ". Mol Biol Cell. 2009. PMID 19386764.
• "Identification of DH IC-2 as a HIF-1 independent protein involved in the adaptive response to hypoxia in tumor cells: A putative role in metastasis. ". Biochim Biophys Acta. 2009. PMID 19744529.
• "Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued.". J Cell Biol. 1995. PMID 8522607.