DUT

DUT
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1Q5H, 1Q5U, 2HQU, 3ARA, 3ARN, 3EHW, 4MZ5, 4MZ6
Dynodwyr
Cyfenwau	DUT, dUTPase, deoxyuridine triphosphatase
Dynodwyr allanol	OMIM: 601266 HomoloGene: 31475 GeneCards: DUT
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • hydrolase activity • RNA binding • magnesium ion binding • dUTP diphosphatase activity Cydrannau o'r gell • extracellular exosome • cnewyllyn cell • mitocondria • nucleoplasm Prosesau biolegol • nucleotide metabolic process • DNA replication • dUTP metabolic process • nucleobase-containing compound metabolic process • nucleobase-containing small molecule interconversion • dUMP biosynthetic process • dUTP catabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1854	n/a
Ensembl	ENSG00000128951	n/a
UniProt	P33316	n/a
RefSeq (mRNA)	NM_001025248 NM_001025249 NM_001948 NM_001330286	n/a
RefSeq (protein)	NP_001020419 NP_001020420 NP_001317215 NP_001939	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DUT yw DUT a elwir hefyd yn Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 15, band 15q21.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DUT.

• dUTPase

Llyfryddiaeth

• "Phosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insights. ". Acta Crystallogr D Biol Crystallogr. 2013. PMID 24311590.
• "Epstein-Barr virus encoded dUTPase containing exosomes modulate innate and adaptive immune responses in human dendritic cells and peripheral blood mononuclear cells. ". PLoS One. 2013. PMID 23894549.
• "Cellular response to efficient dUTPase RNAi silencing in stable HeLa cell lines perturbs expression levels of genes involved in thymidylate metabolism. ". Nucleosides Nucleotides Nucleic Acids. 2011. PMID 21780905.
• "dUTP pyrophosphatase expression correlates with a poor prognosis in hepatocellular carcinoma. ". Liver Int. 2010. PMID 19968781.
• "Kinetic properties and specificity of trimeric Plasmodium falciparum and human dUTPases.". Biochimie. 2010. PMID 19879316.