DUSP5

DUSP5
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2G6Z
Dynodwyr
Cyfenwau	DUSP5, DUSP, HVH3, dual specificity phosphatase 5
Dynodwyr allanol	OMIM: 603069 HomoloGene: 3256 GeneCards: DUSP5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • phosphoprotein phosphatase activity • GO:0001948, GO:0016582 protein binding • protein tyrosine phosphatase activity • MAP kinase tyrosine/serine/threonine phosphatase activity • hydrolase activity • GO:0098519, GO:0098518 phosphatase activity • protein tyrosine/serine/threonine phosphatase activity Cydrannau o'r gell • nucleoplasm • cnewyllyn cell • cytoplasm Prosesau biolegol • GO:0016576 protein dephosphorylation • MAPK cascade • endoderm formation • peptidyl-tyrosine dephosphorylation • GO:0098501, GO:0098502, GO:0006286 dephosphorylation • peptidyl-threonine dephosphorylation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1847	n/a
Ensembl	ENSG00000138166	n/a
UniProt	Q16690	n/a
RefSeq (mRNA)	NM_004419	n/a
RefSeq (protein)	NP_004410	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DUSP5 yw DUSP5 a elwir hefyd yn Dual specificity phosphatase 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 10, band 10q25.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DUSP5.

• DUSP
• HVH3

Llyfryddiaeth

• "Critical Role of the Secondary Binding Pocket in Modulating the Enzymatic Activity of DUSP5 toward Phosphorylated ERKs. ". Biochemistry. 2016. PMID 27739308.
• "Protein expression, characterization and activity comparisons of wild type and mutant DUSP5 proteins. ". BMC Biochem. 2014. PMID 25519881.
• "Down-regulation of dual-specificity phosphatase 5 in gastric cancer by promoter CpG island hypermethylation and its potential role in carcinogenesis. ". Am J Pathol. 2013. PMID 23402999.
• "Crystal structure of the catalytic domain of human DUSP5, a dual specificity MAP kinase protein phosphatase. ". Proteins. 2007. PMID 17078075.
• "Dual-specificity phosphatase 5 (DUSP5) as a direct transcriptional target of tumor suppressor p53.". Oncogene. 2003. PMID 12944906.