DUSP18

DUSP18
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2ESB
Dynodwyr
Cyfenwau	DUSP18, DSP18, DUSP20, LMWDSP20, bK963H5.1, dual specificity phosphatase 18
Dynodwyr allanol	OMIM: 611446 HomoloGene: 34984 GeneCards: DUSP18
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein tyrosine phosphatase activity • MAP kinase tyrosine/serine/threonine phosphatase activity • phosphoprotein phosphatase activity • hydrolase activity • GO:0098519, GO:0098518 phosphatase activity • protein tyrosine/serine/threonine phosphatase activity Cydrannau o'r gell • cytoplasm • cnewyllyn cell • nucleoplasm • mitocondria • bilen • mitochondrial inner membrane Prosesau biolegol • GO:0016576 protein dephosphorylation • peptidyl-tyrosine dephosphorylation • peptidyl-threonine dephosphorylation • GO:0098501, GO:0098502, GO:0006286 dephosphorylation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	150290	n/a
Ensembl	ENSG00000167065	n/a
UniProt	Q8NEJ0	n/a
RefSeq (mRNA)	NM_001304794 NM_001304795 NM_001304796 NM_152511	n/a
RefSeq (protein)	NP_001291723 NP_001291724 NP_001291725 NP_689724	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DUSP18 yw DUSP18 a elwir hefyd yn Dual specificity phosphatase 18 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 22, band 22q12.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DUSP18.

• DSP18
• DUSP20
• LMWDSP20

Llyfryddiaeth

• "Identification and characterization of two novel low-molecular-weight dual specificity phosphatases. ". Biochem Biophys Res Commun. 2002. PMID 12408986.
• "Dual-specificity phosphatases: critical regulators with diverse cellular targets. ". Biochem J. 2009. PMID 19228121.
• "Dual specificity phosphotase 18, interacting with SAPK, dephosphorylates SAPK and inhibits SAPK/JNK signal pathway in vivo. ". Front Biosci. 2006. PMID 16720344.
• "Structure of human DSP18, a member of the dual-specificity protein tyrosine phosphatase family. ". Acta Crystallogr D Biol Crystallogr. 2006. PMID 16699184.
• "Molecular cloning and characterization of a novel dual-specificity phosphatase18 gene from human fetal brain.". Biochim Biophys Acta. 2003. PMID 12591617.