DRD2

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DRD2
Protein DRD2 PDB 1I15.png
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauDRD2, D2DR, D2R, dopamine receptor D2
Dynodwyr allanolOMIM: 126450 HomoloGene: 22561 GeneCards: DRD2
Patrwm RNA pattern
PBB GE DRD2 206590 x at fs.png

PBB GE DRD2 216924 s at fs.png

PBB GE DRD2 211624 s at fs.png
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016574
NM_000795

n/a

RefSeq (protein)

NP_000786
NP_057658
NP_000786.1

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DRD2 yw DRD2 a elwir hefyd yn Dopamine receptor D2, isoform CRA_c (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11q23.2.[2]

Cyfystyron[golygu | golygu cod y dudalen]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DRD2.

  • D2R
  • D2DR

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "The impact of common dopamine D2 receptor gene polymorphisms on D2/3 receptor availability: C957T as a key determinant in putamen and ventral striatum. ". Transl Psychiatry. 2017. PMID 28398340.
  • "Association of the dopamine D2 receptor rs1800497 polymorphism and eating behavior in Chilean children. ". Nutrition. 2017. PMID 28241982.
  • "DRD2 co-expression network and a related polygenic index predict imaging, behavioral and clinical phenotypes linked to schizophrenia. ". Transl Psychiatry. 2017. PMID 28094815.
  • "Activation of D2 Dopamine Receptors in CD133+ve Cancer Stem Cells in Non-small Cell Lung Carcinoma Inhibits Proliferation, Clonogenic Ability, and Invasiveness of These Cells. ". J Biol Chem. 2017. PMID 27920206.
  • "Dopamine-2 receptor extracellular N-terminus regulates receptor surface availability and is the target of human pathogenic antibodies from children with movement and psychiatric disorders.". Acta Neuropathol Commun. 2016. PMID 27908295.

Cyfeiriadau[golygu | golygu cod y dudalen]

  1. "Human PubMed Reference:".
  2. DRD2 - Cronfa NCBI