DPYSL2

DPYSL2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2GSE, 2VM8
Dynodwyr
Cyfenwau	DPYSL2, CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2, dihydropyrimidinase like 2
Dynodwyr allanol	OMIM: 602463 HomoloGene: 74392 GeneCards: DPYSL2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • microtubule binding • dihydropyrimidinase activity • GO:0001948, GO:0016582 protein binding • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds • hydrolase activity • identical protein binding Cydrannau o'r gell • cytoplasm • cytosol • bilen • extracellular exosome • microtubule • Cytosgerbwd • Cellbilen Prosesau biolegol • regulation of neuron differentiation • cell differentiation • endocytosis • regulation of axon extension • nervous system development • multicellular organism development • brain development • cytoskeleton organization • nucleobase-containing compound metabolic process • GO:0072468 signal transduction • axon guidance • pyrimidine nucleobase catabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1808	n/a
Ensembl	ENSG00000092964	n/a
UniProt	Q16555	n/a
RefSeq (mRNA)	NM_001386 NM_001197293 NM_001244604	n/a
RefSeq (protein)	NP_001184222 NP_001231533 NP_001377	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DPYSL2 yw DPYSL2 a elwir hefyd yn Dihydropyrimidinase like 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 8, band 8p21.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DPYSL2.

• DRP2
• N2A3
• CRMP2
• DRP-2
• ULIP2
• CRMP-2
• DHPRP2
• ULIP-2

Llyfryddiaeth

• "Collapsin response mediator protein 2: high-resolution crystal structure sheds light on small-molecule binding, post-translational modifications, and conformational flexibility. ". Amino Acids. 2017. PMID 28044206.
• "Identification of a dithiol-disulfide switch in collapsin response mediator protein 2 (CRMP2) that is toggled in a model of neuronal differentiation. ". J Biol Chem. 2013. PMID 24133216.
• "Association between DPYSL2 gene polymorphisms and alcohol dependence in Caucasian samples. ". J Neural Transm (Vienna). 2014. PMID 23846846.
• "Collapsin response mediator protein 2 is involved in regulating breast cancer progression. ". Breast Cancer. 2014. PMID 23381229.
• "Phosphorylated tubulin adaptor protein CRMP-2 as prognostic marker and candidate therapeutic target for NSCLC.". Int J Cancer. 2013. PMID 23023514.