DPP6

DPP6
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1XFD
Dynodwyr
Cyfenwau	DPP6, DPPX, VF2, MRD33, DPL1, dipeptidyl peptidase like 6
Dynodwyr allanol	OMIM: 126141 HomoloGene: 22560 GeneCards: DPP6
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • potassium channel regulator activity • serine-type peptidase activity • dipeptidyl-peptidase activity Cydrannau o'r gell • integral component of membrane • Cellbilen • bilen • voltage-gated potassium channel complex Prosesau biolegol • protein localization to plasma membrane • regulation of potassium ion transmembrane transport • proteolysis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1804	n/a
Ensembl	ENSG00000130226 ENSG00000282974	n/a
UniProt	P42658 Q8IYG9	n/a
RefSeq (mRNA)	NM_001039350 NM_001290252 NM_001290253 NM_001936 NM_130797	n/a
RefSeq (protein)	NP_001034439 NP_001277181 NP_001277182 NP_001927 NP_570629 NP_001351426 NP_001351427 NP_001351428 NP_001351429 NP_001351430 NP_001351431 NP_001277182.1 NP_570629.2 NP_001034439.1 NP_001277181.1 NP_001927.3 NP_570629.2	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DPP6 yw DPP6 a elwir hefyd yn Dipeptidyl-peptidase 6 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7q36.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DPP6.

• VF2
• DPL1
• DPPX
• MRD33

Llyfryddiaeth

• "Detailed characterization of familial idiopathic ventricular fibrillation linked to the DPP6 locus. ". Heart Rhythm. 2016. PMID 26681609.
• "DPP6 domains responsible for its localization and function. ". J Biol Chem. 2014. PMID 25190807.
• "DPP6 gene disruption in a family with Gilles de la Tourette syndrome. ". Neurogenetics. 2014. PMID 25129042.
• "Loss-of-function variation in the DPP6 gene is associated with autosomal dominant microcephaly and mental retardation. ". Eur J Med Genet. 2013. PMID 23832105.
• "Unique cardiac Purkinje fiber transient outward current β-subunit composition: a potential molecular link to idiopathic ventricular fibrillation.". Circ Res. 2013. PMID 23532596.