DPEP1

DPEP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1ITQ, 1ITU
Dynodwyr
Cyfenwau	DPEP1, MBD1, MDP, RDP, dipeptidase 1 (renal), dipeptidase 1
Dynodwyr allanol	OMIM: 179780 HomoloGene: 80192 GeneCards: DPEP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • metallodipeptidase activity • zinc ion binding • metal ion binding • cysteine-type endopeptidase inhibitor activity involved in apoptotic process • GO:0070122 peptidase activity • GPI anchor binding • modified amino acid binding • GO:0001948, GO:0016582 protein binding • metalloexopeptidase activity • hydrolase activity • metallopeptidase activity • dipeptidyl-peptidase activity • dipeptidase activity Cydrannau o'r gell • cell projection • bilen • Cellbilen • apical part of cell • apical plasma membrane • anchored component of membrane • extracellular exosome • microvillus membrane • extracellular space • cnewyllyn cell • cell junction Prosesau biolegol • cellular response to calcium ion • negative regulation of cysteine-type endopeptidase activity involved in apoptotic process • leukotriene metabolic process • glutathione metabolic process • antibiotic metabolic process • negative regulation of apoptotic process • proteolysis • negative regulation of cell migration • xenobiotic metabolic process • cellular response to nitric oxide • homocysteine metabolic process • cellular lactam catabolic process • GO:0097285 apoptotic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1800	n/a
Ensembl	ENSG00000015413	n/a
UniProt	P16444	n/a
RefSeq (mRNA)	NM_001128141 NM_004413	n/a
RefSeq (protein)	NP_001121613 NP_004404	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DPEP1 yw DPEP1 a elwir hefyd yn Dipeptidase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16q24.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DPEP1.

• MDP
• RDP
• MBD1

Llyfryddiaeth

• "Dehydropeptidase 1 promotes metastasis through regulation of E-cadherin expression in colon cancer. ". Oncotarget. 2016. PMID 26824987.
• "Reintroduction of a Homocysteine Level-Associated Allele into East Asians by Neanderthal Introgression. ". Mol Biol Evol. 2015. PMID 26392408.
• "Dipeptidase 1 (DPEP1) is a marker for the transition from low-grade to high-grade intraepithelial neoplasia and an adverse prognostic factor in colorectal cancer. ". Br J Cancer. 2013. PMID 23839495.
• "DPEP1 inhibits tumor cell invasiveness, enhances chemosensitivity and predicts clinical outcome in pancreatic ductal adenocarcinoma. ". PLoS One. 2012. PMID 22363658.
• "Distinguishing primary from secondary mucinous ovarian tumors: an algorithm using the novel marker DPEP1.". Mod Pathol. 2011. PMID 21076463.