DMTN

DMTN
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1QZP, 1ZV6
Dynodwyr
Cyfenwau	DMTN, DMT, EPB49, dematin actin binding protein
Dynodwyr allanol	OMIM: 125305 HomoloGene: 1496 GeneCards: DMTN
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • spectrin binding • GO:0001948, GO:0016582 protein binding • actin binding • signaling receptor binding • protein self-association • actin filament binding Cydrannau o'r gell • cytoplasm • cytosol • cell projection • bilen • cortical cytoskeleton • Cellbilen • platelet dense tubular network membrane • cell projection membrane • Microffilament • actin cytoskeleton • spectrin-associated cytoskeleton • perinuclear region of cytoplasm • endomembrane system • Cytosgerbwd • GO:0097483, GO:0097481 postsynaptic density • GO:0016023 cytoplasmic vesicle Prosesau biolegol • negative regulation of cell-substrate adhesion • regulation of lamellipodium assembly • cellular response to calcium ion • regulation of filopodium assembly • actin filament reorganization • regulation of actin cytoskeleton organization • negative regulation of peptidyl-threonine phosphorylation • positive regulation of wound healing • actin filament bundle assembly • positive regulation of substrate adhesion-dependent cell spreading • negative regulation of protein targeting to membrane • negative regulation of peptidyl-tyrosine phosphorylation • positive regulation of blood coagulation • calcium-mediated signaling using extracellular calcium source • cytoskeleton organization • actin filament capping • transmembrane transport • negative regulation of peptidyl-serine phosphorylation • positive regulation of integrin-mediated signaling pathway • protein secretion by platelet • negative regulation of substrate adhesion-dependent cell spreading • calcium-mediated signaling using intracellular calcium source • positive regulation of fibroblast migration • negative regulation of focal adhesion assembly • actin cytoskeleton organization • positive regulation of platelet aggregation • cellular response to cAMP • erythrocyte development • regulation of cell shape • GO:0034622 protein-containing complex assembly • lamellipodium assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2039	n/a
Ensembl	ENSG00000158856	n/a
UniProt	Q08495	n/a
RefSeq (mRNA)	NM_001114135 NM_001114136 NM_001114137 NM_001114138 NM_001114139 NM_001302816 NM_001302817 NM_001978 NM_001323378 NM_001323380 NM_001323381 NM_001323382 NM_001323383 NM_001323384 NM_001323385 NM_001323387 NM_001323388 NM_001323389 NM_001323390 NM_001323391 NM_001323392 NM_001323393 NM_001323394 NM_001323395 NM_001323396 NM_001323397 NM_001323398 NM_001323399 NM_001323400 NM_001323401 NM_001323379 NM_001387723 NM_001387726 NM_001387727 NM_001387728 NM_001387730 NM_001387732 NM_001387734 NM_001387735 NM_001387736 NM_001387737 NM_001387742 NM_001387743 NM_001387744 NM_001387745 NM_001387750 NM_001387751 NM_001387752 NM_001387753 NM_001387754 NM_001387755 NM_001387756 NM_001387757	n/a
RefSeq (protein)	NP_001107607 NP_001107608 NP_001107609 NP_001107610 NP_001107611 NP_001289745 NP_001289746 NP_001310307 NP_001310308 NP_001310309 NP_001310310 NP_001310311 NP_001310312 NP_001310313 NP_001310314 NP_001310316 NP_001310317 NP_001310318 NP_001310319 NP_001310320 NP_001310321 NP_001310322 NP_001310323 NP_001310324 NP_001310325 NP_001310326 NP_001310327 NP_001310328 NP_001310329 NP_001310330 NP_001969	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DMTN yw DMTN a elwir hefyd yn Dematin actin binding protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 8, band 8p21.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DMTN.

• DMT
• EPB49

Llyfryddiaeth

• "Dematin, a human erythrocyte cytoskeletal protein, is a substrate for a recombinant FIKK kinase from Plasmodium falciparum. ". Mol Biochem Parasitol. 2013. PMID 23973789.
• "Proteomic analysis shows the upregulation of erythrocyte dematin in zinc-restricted human subjects. ". Am J Clin Nutr. 2012. PMID 22456662.
• "Comparison of fast backbone dynamics at amide nitrogen and carbonyl sites in dematin headpiece C-terminal domain and its S74E mutant. ". J Biomol NMR. 2010. PMID 20396930.
• "Phosphorylation-induced changes in backbone dynamics of the dematin headpiece C-terminal domain. ". J Biomol NMR. 2009. PMID 19030997.
• "A phosphorylation-induced conformation change in dematin headpiece.". Structure. 2006. PMID 16472756.