DHX9 Dynodwyr Cyfenwau DHX9 Dynodwyr allanol OMIM: 603115 HomoloGene: 1039 GeneCards: DHX9 Ontoleg y genyn Gweithrediad moleciwlaidd • RNA helicase activity • nucleotide binding • GO:0008026 helicase activity • GO:0001948, GO:0016582 protein binding • nucleic acid binding • hydrolase activity • RNA binding • DNA binding • single-stranded DNA binding • double-stranded RNA binding • single-stranded RNA binding • nucleoside-triphosphatase activity • chromatin DNA binding • GO:0033681 3'-5' DNA/RNA helicase activity • GO:0034459 3'-5' RNA helicase activity • triplex DNA binding • nucleoside-triphosphate diphosphatase activity • importin-alpha family protein binding • single-stranded 3'-5' DNA helicase activity • siRNA binding • mRNA binding • RNA stem-loop binding • polysome binding • promoter-specific chromatin binding • RNA polymerase II complex binding • regulatory region RNA binding • GO:0001104 transcription coregulator activity • GO:0001105 transcription coactivator activity • DNA replication origin binding • double-stranded DNA binding • GO:0004003 DNA helicase activity • ATP binding • ATPase activity • RNA polymerase binding • GO:0043140 3'-5' DNA helicase activity • RISC complex binding • sequence-specific mRNA binding • metal ion binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding Cydrannau o'r gell • CRD-mediated mRNA stability complex • cytosol • centrosome • bilen • cytoplasmic ribonucleoprotein granule • cnewyllyn cell • nucleolus • perichromatin fibrils • cytoplasm • nuclear stress granule • nuclear body • polysomal ribosome • polysome • actin cytoskeleton • RISC-loading complex • nucleoplasm • microtubule organizing center • Cytosgerbwd • GO:0009327 protein-containing complex • ribonucleoprotein complex Prosesau biolegol • CRD-mediated mRNA stabilization • mRNA splicing, via spliceosome • GO:0033168, GO:0036404, GO:1902360 RNA processing • proses rythmig • protein localization to cytoplasmic stress granule • osteoblast differentiation • positive regulation of type I interferon production • RNA secondary structure unwinding • GO:1900404 positive regulation of DNA repair • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • positive regulation of response to cytokine stimulus • cellular response to exogenous dsRNA • alternative mRNA splicing, via spliceosome • DNA-templated viral transcription • positive regulation of viral transcription • positive regulation of viral translation • positive regulation of cytoplasmic translation • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • DNA duplex unwinding • positive regulation of DNA replication • positive regulation of fibroblast proliferation • regulation of mRNA processing • positive regulation of NF-kappaB transcription factor activity • cellular response to tumor necrosis factor • positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity • regulation of cytoplasmic translation • positive regulation of interleukin-18 production • G-quadruplex DNA unwinding • positive regulation of innate immune response • positive regulation of RNA export from nucleus • regulation of defense response to virus by host • positive regulation of inflammatory response • pyroptosis • GO:0035087, GO:0035280, GO:0070923 small RNA loading onto RISC • positive regulation of polysome binding • GO:1905618 positive regulation of gene silencing by miRNA • immune system process • DNA replication • transcription, DNA-templated • DNA-templated transcription, termination • GO:0009373 regulation of transcription, DNA-templated • mRNA processing • regulation of translation • GO:0015915 transport • inflammatory response • RNA splicing • gene silencing • innate immune response • mRNA transport Sources:Amigo / QuickGO
Orthologau Species Bod dynol Llygoden Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Lleoliad (UCSC) n/a n/a PubMed search[1] n/a Wicidata
Protein sy'n cael ei godio yn y corff dynol gan y genyn DHX9 yw DHX9 a elwir hefyd yn DExH-box helicase 9 (Saesneg). Segment o DNA yw'r genyn , sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q25.3.[2]
Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DHX9.
"The RNA helicase A in malignant transformation. ". Oncotarget . 2016. PMID 26885691 . "Genotoxic stress inhibits Ewing sarcoma cell growth by modulating alternative pre-mRNA processing of the RNA helicase DHX9. ". Oncotarget . 2015. PMID 26450900 . "Role of the OB-fold of RNA helicase A in the synthesis of HIV-1 RNA. ". Biochim Biophys Acta . 2014. PMID 25149208 . "Different activities of the conserved lysine residues in the double-stranded RNA binding domains of RNA helicase A in vitro and in the cell. ". Biochim Biophys Acta . 2014. PMID 24726449 . "Roles of the linker region of RNA helicase A in HIV-1 RNA metabolism. ". PLoS One . 2013. PMID 24223160 . 
