DHPS

DHPS
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1DHS, 1RLZ, 1ROZ, 1RQD
Dynodwyr
Cyfenwau	DHPS, deoxyhypusine synthase, DHS, DS, MIG13, NEDSSWI
Dynodwyr allanol	OMIM: 600944 HomoloGene: 1453 GeneCards: DHPS
EC number	2.5.1.46
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • GO:0001948, GO:0016582 protein binding • identical protein binding • deoxyhypusine synthase activity Cydrannau o'r gell • cytosol • cytoplasm Prosesau biolegol • protein homotetramerization • protein biosynthesis • positive regulation of T cell proliferation • glucose homeostasis • positive regulation of cell population proliferation • spermidine metabolic process • spermidine catabolic process • peptidyl-lysine modification to peptidyl-hypusine Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1725	n/a
Ensembl	ENSG00000095059	n/a
UniProt	P49366	n/a
RefSeq (mRNA)	NM_001206974 NM_001930 NM_013406 NM_001369691 NM_001369692 NM_001369693	n/a
RefSeq (protein)	NP_001193903 NP_001921 NP_037538 NP_001356620 NP_001356621 NP_001356622	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DHPS yw DHPS a elwir hefyd yn Deoxyhypusine synthase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19p13.13.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DHPS.

• DS
• DHS
• MIG13

Llyfryddiaeth

• "Functional significance of eIF5A and its hypusine modification in eukaryotes. ". Amino Acids. 2010. PMID 19997760.
• "Protein kinase CK2 phosphorylates and interacts with deoxyhypusine synthase in HeLa cells. ". Exp Mol Med. 2003. PMID 14749535.
• "Localization and genomic structure of human deoxyhypusine synthase gene on chromosome 19p13.2-distal 19p13.1. ". Gene. 1998. PMID 9666110.
• "Crystal structure of the NAD complex of human deoxyhypusine synthase: an enzyme with a ball-and-chain mechanism for blocking the active site. ". Structure. 1998. PMID 9493264.
• "The gene coding for human deoxyhypusine synthase (DHPS) maps to chromosome 19p13.11-p13.12.". Genomics. 1996. PMID 8812510.