DEK

DEK
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1Q1V, 2JX3
Dynodwyr
Cyfenwau	DEK, D6S231E, DEK proto-oncogene
Dynodwyr allanol	OMIM: 125264 HomoloGene: 2593 GeneCards: DEK
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • GO:0031493 histone binding • chromatin binding • RNA binding Cydrannau o'r gell • nucleoplasm • contractile fiber • cnewyllyn cell Prosesau biolegol • epigenetic maintenance of chromatin in transcription-competent conformation • viral genome replication • regulation of double-strand break repair via nonhomologous end joining • transcription by RNA polymerase II • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • regulation of double-strand break repair • GO:0072468 signal transduction • chromatin remodeling • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7913	n/a
Ensembl	ENSG00000124795	n/a
UniProt	P35659	n/a
RefSeq (mRNA)	NM_001134709 NM_003472	n/a
RefSeq (protein)	NP_001128181 NP_003463	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DEK yw DEK a elwir hefyd yn DEK proto-oncogene (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p22.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DEK.

• D6S231E

Llyfryddiaeth

• "DEK protein overexpression predicts poor prognosis in pancreatic ductal adenocarcinoma. ". Oncol Rep. 2017. PMID 27959420.
• "DEK oncogene is overexpressed during melanoma progression. ". Pigment Cell Melanoma Res. 2017. PMID 27893188.
• "DEK proto-oncogene is highly expressed in astrocytic tumors and regulates glioblastoma cell proliferation and apoptosis. ". Tumour Biol. 2017. PMID 28670979.
• "DEK protein level is a biomarker of CD138positive normal and malignant plasma cells. ". PLoS One. 2017. PMID 28558048.
• "Overexpression of the human DEK oncogene reprograms cellular metabolism and promotes glycolysis.". PLoS One. 2017. PMID 28558019.