DDX39A

DDX39A
Dynodwyr
Cyfenwau	DDX39A, BAT1, BAT1L, DDX39, DDXL, URH49, DEAD-box helicase 39A, DExD-box helicase 39A
Dynodwyr allanol	HomoloGene: 68487 GeneCards: DDX39A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0008026 helicase activity • nucleotide binding • GO:0001948, GO:0016582 protein binding • nucleic acid binding • hydrolase activity • ATP binding • ATPase activity • identical protein binding • RNA binding Cydrannau o'r gell • bilen • spliceosomal complex • cytoplasm • cnewyllyn cell • nucleoplasm • nuclear speck • nucleolus Prosesau biolegol • RNA splicing • mRNA splicing, via spliceosome • mRNA processing • mRNA export from nucleus • cellular response to DNA damage stimulus • RNA secondary structure unwinding • regulation of gene expression • RNA export from nucleus • termination of RNA polymerase II transcription • mRNA 3'-end processing Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10212	n/a
Ensembl	ENSG00000123136	n/a
UniProt	O00148	n/a
RefSeq (mRNA)	NM_001204057 NM_005804 NM_138998	n/a
RefSeq (protein)	NP_005795	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DDX39A yw DDX39A a elwir hefyd yn ATP-dependent RNA helicase DDX39A a DExD-box helicase 39a (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19p13.12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DDX39A.

• BAT1
• DDXL
• BAT1L
• DDX39
• URH49

Llyfryddiaeth

• "Clinical proteomics identified ATP-dependent RNA helicase DDX39 as a novel biomarker to predict poor prognosis of patients with gastrointestinal stromal tumor. ". J Proteomics. 2012. PMID 22119546.
• "Requirement of DDX39 DEAD box RNA helicase for genome integrity and telomere protection. ". Aging Cell. 2011. PMID 21388492.
• "Identification of DDX39A as a Potential Biomarker for Unfavorable Neuroblastoma Using a Proteomic Approach. ". Pediatr Blood Cancer. 2016. PMID 26469522.
• "Up-regulation of DDX39 in human malignant pleural mesothelioma cell lines compared to normal pleural mesothelial cells. ". Anticancer Res. 2013. PMID 23749908.
• "DDX39 acts as a suppressor of invasion for bladder cancer.". Cancer Sci. 2012. PMID 22494014.