DDX20

DDX20
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2OXC, 3B7G
Dynodwyr
Cyfenwau	DDX20, DP103, GEMIN3, DEAD-box helicase 20
Dynodwyr allanol	OMIM: 606168 HomoloGene: 5214 GeneCards: DDX20
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • protein-macromolecule adaptor activity • nucleotide binding • GO:0008026 helicase activity • protein domain specific binding • histone deacetylase binding • GO:0001948, GO:0016582 protein binding • nucleic acid binding • hydrolase activity • ATP binding Cydrannau o'r gell • SMN-Sm protein complex • cytosol • bilen • transcription repressor complex • nucleoplasm • SMN complex • RNA polymerase II transcription repressor complex • Cytosgerbwd • cnewyllyn cell • gemini of coiled bodies • cytoplasm • nuclear body • nucleolus Prosesau biolegol • GO:0033168, GO:0036404, GO:1902360 RNA processing • spliceosomal tri-snRNP complex assembly • mRNA processing • regulation of steroid biosynthetic process • GO:1901227 negative regulation of transcription by RNA polymerase II • oogenesis • spliceosomal snRNP assembly • RNA secondary structure unwinding • RNA splicing • positive regulation of apoptotic process • GO:0045996 negative regulation of transcription, DNA-templated • negative regulation of cell population proliferation • import into nucleus Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	11218	n/a
Ensembl	ENSG00000064703	n/a
UniProt	Q9UHI6	n/a
RefSeq (mRNA)	NM_007204	n/a
RefSeq (protein)	NP_009135	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DDX20 yw DDX20 a elwir hefyd yn DEAD-box helicase 20 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p13.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DDX20.

• DP103
• GEMIN3

Llyfryddiaeth

• "Pseudophosphorylated αB-crystallin is a nuclear chaperone imported into the nucleus with help of the SMN complex. ". PLoS One. 2013. PMID 24023879.
• "A miRNA machinery component DDX20 controls NF-κB via microRNA-140 function. ". Biochem Biophys Res Commun. 2012. PMID 22445758.
• "DEAD-box helicase DP103 defines metastatic potential of human breast cancers. ". J Clin Invest. 2014. PMID 25083991.
• "Evaluation of genetic variants in microRNA-related genes and risk of bladder cancer. ". Cancer Res. 2008. PMID 18381463.
• "Characterization of DP103, a novel DEAD box protein that binds to the Epstein-Barr virus nuclear proteins EBNA2 and EBNA3C.". J Biol Chem. 1999. PMID 10383418.