DCK
Protein sy'n cael ei godio yn y corff dynol gan y genyn DCK yw DCK a elwir hefyd yn Deoxycytidine kinase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 4, band 4q13.3.[2]
Llyfryddiaeth[golygu | golygu cod]
- "dCK Expression and Gene Polymorphism With Gemcitabine Chemosensitivity in Patients With Pancreatic Ductal Adenocarcinoma: A Strobe-Compliant Observational Study. ". Medicine (Baltimore). 2016. PMID 26962792.
- "Potent Sensitisation of Cancer Cells to Anticancer Drugs by a Quadruple Mutant of the Human Deoxycytidine Kinase. ". PLoS One. 2015. PMID 26485161.
- "Acquisition of chemoresistance to gemcitabine is induced by a loss-of-function missense mutation of DCK. ". Biochem Biophys Res Commun. 2015. PMID 26196746.
- "Impact of single nucleotide polymorphisms of cytarabine metabolic genes on drug toxicity in childhood acute lymphoblastic leukemia. ". Pediatr Blood Cancer. 2015. PMID 25557962.
- "Hypoxia-induced deoxycytidine kinase contributes to epithelial proliferation in pulmonary fibrosis.". Am J Respir Crit Care Med. 2014. PMID 25358054.