DAPK1

DAPK1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1IG1, 1JKK, 1JKL, 1JKS, 1JKT, 1P4F, 1WVX, 1WVY, 1YR5, 2W4J, 2W4K, 2X0G, 2XUU, 2XZS, 2Y0A, 2Y4P, 2Y4V, 2YAK, 3DFC, 3DGK, 3EH9, 3EHA, 3F5G, 3F5U, 3GU4, 3GU5, 3GU6, 3GU7, 3GU8, 3GUB, 3ZXT, 4B4L, 4PF4, 4TL0, 4TXC, 4UV0, 4YO4, 4YPD, 5AUW, 5AUU, 5AV1, 5AUY, 5AUT, 5AUX, 5AUV, 5AUZ, 5AV0, 5AV4, 5AV2, 5AV3
Dynodwyr
Cyfenwau	DAPK1, DAPK, death associated protein kinase 1, ROCO3
Dynodwyr allanol	OMIM: 600831 HomoloGene: 3626 GeneCards: DAPK1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • GTP binding • syntaxin-1 binding • kinase activity • GO:0001948, GO:0016582 protein binding • identical protein binding • calmodulin-dependent protein kinase activity • protein serine/threonine kinase activity • calmodulin binding • ATP binding • protein kinase activity Cydrannau o'r gell • Cellbilen • actin cytoskeleton • Cytosgerbwd • cytoplasm • cnewyllyn cell Prosesau biolegol • regulation of apoptotic process • negative regulation of translation • phosphorylation • negative regulation of apoptotic process • positive regulation of cysteine-type endopeptidase activity involved in apoptotic process • regulation of autophagy • negative regulation of extrinsic apoptotic signaling pathway via death domain receptors • apoptotic signaling pathway • protein autophosphorylation • regulation of translation • extrinsic apoptotic signaling pathway via death domain receptors • GO:0072468 signal transduction • GO:0097285 apoptotic process • regulation of NMDA receptor activity • protein phosphorylation • positive regulation of autophagy • GO:0007243 intracellular signal transduction • cellular response to interferon-gamma • cellular response to hydroperoxide Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1612	n/a
Ensembl	ENSG00000196730	n/a
UniProt	P53355	n/a
RefSeq (mRNA)	NM_001288729 NM_001288730 NM_001288731 NM_004938	n/a
RefSeq (protein)	NP_001275658 NP_001275659 NP_001275660 NP_004929	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DAPK1 yw DAPK1 a elwir hefyd yn Death associated protein kinase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9q21.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DAPK1.

• DAPK
• ROCO3

Llyfryddiaeth

• "Correlation of DAPK1 methylation and the risk of gastrointestinal cancer: A systematic review and meta-analysis. ". PLoS One. 2017. PMID 28934284.
• "The prognostic significance of DAPK1 in bladder cancer. ". PLoS One. 2017. PMID 28388658.
• "Association between promoter methylation of DAPK gene and HNSCC: A meta-analysis. ". PLoS One. 2017. PMID 28249042.
• "DAPK Promoter Methylation and Bladder Cancer Risk: A Systematic Review and Meta-Analysis. ". PLoS One. 2016. PMID 27907054.
• "DAPK promoter methylation status correlates with tumor metastasis and poor prognosis in patients with non-small cell lung cancer.". Cancer Biomark. 2015. PMID 26406950.