DAAM1

DAAM1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2J1D, 2Z6E
Dynodwyr
Cyfenwau	DAAM1, dishevelled associated activator of morphogenesis 1
Dynodwyr allanol	OMIM: 606626 HomoloGene: 36635 GeneCards: DAAM1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • actin binding • GO:0001948, GO:0016582 protein binding • identical protein binding Cydrannau o'r gell • Cellbilen • bilen • stress fiber • ciliary basal body • motile cilium • cytoplasm • cytosol • Cytosgerbwd • cell projection Prosesau biolegol • actin cytoskeleton organization • cellular component organization • Wnt signaling pathway, planar cell polarity pathway • Wnt signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23002	n/a
Ensembl	ENSG00000100592	n/a
UniProt	Q9Y4D1	n/a
RefSeq (mRNA)	NM_001270520 NM_014992	n/a
RefSeq (protein)	NP_001257449 NP_055807	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn DAAM1 yw DAAM1 a elwir hefyd yn Dishevelled associated activator of morphogenesis 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 14, band 14q23.1.

Llyfryddiaeth

• "DAAM1 is a formin required for centrosome re-orientation during cell migration. ". PLoS One. 2010. PMID 20927366.
• "Activation of the planar cell polarity formin DAAM1 leads to inhibition of endothelial cell proliferation, migration, and angiogenesis. ". Proc Natl Acad Sci U S A. 2010. PMID 20351293.
• "Implication of overexpression of dishevelled-associated activator of morphogenesis 1 (Daam-1) for the pathogenesis of human Idiopathic Pulmonary Arterial Hypertension (IPAH). ". Diagn Pathol. 2017. PMID 28288669.
• "Daam1 is a regulator of filopodia formation and phagocytic uptake of Borrelia burgdorferi by primary human macrophages. ". FASEB J. 2014. PMID 24696301.
• "Deletion of a single-copy DAAM1 gene in congenital heart defect: a case report.". BMC Med Genet. 2012. PMID 22857009.