CYTH2

CYTH2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1PBV, 1R8M, 1R8Q, 1R8S, 1S9D, 4JMI, 4JMO, 4JWL, 4JXH, 4L5M, 4Z21
Dynodwyr
Cyfenwau	CYTH2, ARNO, CTS18, CTS18.1, PSCD2, PSCD2L, SEC7L, Sec7p-L, Sec7p-like, cytohesin 2, cytohesin-2
Dynodwyr allanol	OMIM: 602488 HomoloGene: 32116 GeneCards: CYTH2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • inositol 1,4,5 trisphosphate binding • GO:0001948, GO:0016582 protein binding • guanyl-nucleotide exchange factor activity • lipid binding Cydrannau o'r gell • cytoplasm • growth cone • Cellbilen • cell projection • bilen • Golgi membrane • cytosol • adherens junction • bicellular tight junction • cell junction Prosesau biolegol • regulation of ARF protein signal transduction • endocytosis • actin cytoskeleton organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9266	n/a
Ensembl	ENSG00000105443	n/a
UniProt	Q99418	n/a
RefSeq (mRNA)	NM_004228 NM_017457	n/a
RefSeq (protein)	NP_004219 NP_059431	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CYTH2 yw CYTH2 a elwir hefyd yn Cytohesin-2 a Cytohesin 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19q13.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CYTH2.

• ARNO
• CTS18
• PSCD2
• SEC7L
• PSCD2L
• CTS18.1
• Sec7p-L
• Sec7p-like
• cytohesin-2

Llyfryddiaeth

• "Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability. ". Nature. 2012. PMID 23143332.
• "Salmonella virulence effector SopE and Host GEF ARNO cooperate to recruit and activate WAVE to trigger bacterial invasion. ". Cell Host Microbe. 2012. PMID 22341462.
• "Cytohesins/ARNO: the function in colorectal cancer cells. ". PLoS One. 2014. PMID 24618737.
• "Effect of Ser392 phosphorylation on the structure and dynamics of the polybasic domain of ADP ribosylation factor nucleotide site opener protein: a molecular simulation study. ". Biochemistry. 2013. PMID 24083777.
• "Cytohesin-2 as a novel prognostic marker for hepatocellular carcinoma.". Oncol Rep. 2013. PMID 23545718.