CYP2C19

CYP2C19
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4GQS
Dynodwyr
Cyfenwau	CYP2C19, CPCJ, CYP2C, CYPIIC17, CYPIIC19, P450C2C, P450IIC19, cytochrome P450 family 2 subfamily C member 19
Dynodwyr allanol	OMIM: 124020 HomoloGene: 133565 GeneCards: CYP2C19
EC number	1.14.14.51
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • iron ion binding • oxygen binding • arachidonic acid epoxygenase activity • metal ion binding • monooxygenase activity • steroid hydroxylase activity • heme binding • GO:0050602 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen • enzyme binding • oxidoreductase activity • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen Cydrannau o'r gell • organelle membrane • endoplasmic reticulum membrane • bilen • intracellular membrane-bounded organelle • Reticwlwm endoplasmig • cytoplasm Prosesau biolegol • steroid metabolic process • epoxygenase P450 pathway • omega-hydroxylase P450 pathway • heterocycle metabolic process • monoterpenoid metabolic process • xenobiotic metabolic process • organic acid metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1557	n/a
Ensembl	ENSG00000165841	n/a
UniProt	P33261	n/a
RefSeq (mRNA)	NM_000769	n/a
RefSeq (protein)	NP_000760	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CYP2C19 yw CYP2C19 a elwir hefyd yn Cytochrome P450 family 2 subfamily C member 19 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 10, band 10q23.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CYP2C19.

• CPCJ
• CYP2C
• P450C2C
• CYPIIC17
• CYPIIC19
• P450IIC19

Llyfryddiaeth

• "[Association of ITGB3, P2RY12, and CYP2C19 gene polymorphisms with platelet functional activity in patients with coronary heart disease during dual antiplatelet therapy]. ". Ter Arkh. 2017. PMID 28631703.
• "Effects of CYP2C19 Genetic Polymorphisms on PK/PD Responses of Omeprazole in Korean Healthy Volunteers. ". J Korean Med Sci. 2017. PMID 28378544.
• "Administration of Ticagrelor and Double-Dose Clopidogrel Based on Platelet Reactivity Determined by VerifyNow-P2Y12 for Chinese Subjects After Elective PCI. ". Int Heart J. 2017. PMID 28321022.
• "Impact of Glycemic Control on Efficacy of Clopidogrel in Transient Ischemic Attack or Minor Stroke Patients With CYP2C19Genetic Variants. ". Stroke. 2017. PMID 28289237.
• "Characterization of Three CYP2C19 Gene Variants by MassARRAY and Point of Care Techniques: Experience from a Czech Centre.". Arch Immunol Ther Exp (Warsz). 2016. PMID 28083610.