CYP2A13

CYP2A13
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2P85, 2PG5, 2PG6, 2PG7, 3T3S, 4EJG, 4EJH, 4EJI
Dynodwyr
Cyfenwau	CYP2A13, CPAD, CYP2A, CYPIIA13, cytochrome P450 family 2 subfamily A member 13
Dynodwyr allanol	OMIM: 608055 HomoloGene: 85917 GeneCards: CYP2A13
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • iron ion binding • oxidoreductase activity • aromatase activity • arachidonic acid epoxygenase activity • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen • heme binding • GO:0050602 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen • metal ion binding • coumarin 7-hydroxylase activity • steroid hydroxylase activity • monooxygenase activity Cydrannau o'r gell • organelle membrane • endoplasmic reticulum membrane • Reticwlwm endoplasmig • bilen • intracellular membrane-bounded organelle • cytoplasm Prosesau biolegol • xenobiotic metabolic process • epoxygenase P450 pathway • coumarin metabolic process • organic acid metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1553	n/a
Ensembl	ENSG00000197838	n/a
UniProt	Q16696	n/a
RefSeq (mRNA)	NM_000766	n/a
RefSeq (protein)	NP_000757	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CYP2A13 yw CYP2A13 a elwir hefyd yn Cytochrome P450 family 2 subfamily A member 13 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19q13.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CYP2A13.

• CPAD
• CYP2A
• CYPIIA13

Llyfryddiaeth

• "CYP2A13 Genetic Polymorphisms in Relation to the Risk of Bladder Cancer in Japanese Smokers. ". Biol Pharm Bull. 2016. PMID 27725446.
• "In vitro metabolism of N'-Nitrosonornicotine catalyzed by cytochrome P450 2A13 and its inhibition by nicotine, N'-Nitrosoanatabine and N'-Nitrosoanabasine. ". Chem Biol Interact. 2016. PMID 27567546.
• "Suppression of pulmonary CYP2A13 expression by carcinogen-induced lung tumorigenesis in a CYP2A13-humanized mouse model. ". Drug Metab Dispos. 2015. PMID 25710941.
• "Generation and characterization of a novel CYP2A13--transgenic mouse model. ". Drug Metab Dispos. 2014. PMID 24907355.
• "Cytochrome P450 2A13 mediates the neoplastic transformation of human bronchial epithelial cells at a low concentration of aflatoxin B1.". Int J Cancer. 2014. PMID 24114584.