CYP19A1

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Cytochrome P450 family 19 subfamily A member 1
Dynodwyr
Cyfenwauestrogen synthasemicrosomal monooxygenaseestrogen synthetasearomataseCYP19A1cytochrome P-450AROMCytochrome P450 family 19 subfamily A member 1cytochrome P450subfamily XIX (aromatization of androgens)CYPXIXcytochrome P450 19A1cytochrome P450family 19subfamily Apolypeptide 1flavoprotein-linked monooxygenase
Dynodwyr allanolGeneCards: [1]
Patrwm RNA pattern
PBB GE PGR 208305 at tn.png
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

n/a

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Lleoliad (UCSC)n/an/a
PubMed searchn/an/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CYP19A1 yw CYP19A1 a elwir hefyd yn Aromatase a Cytochrome P450 family 19 subfamily A member 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 15, band 15q21.2.[1]

Cyfystyron[golygu | golygu cod y dudalen]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CYP19A1.

  • ARO
  • ARO1
  • CPV1
  • CYAR
  • CYP19
  • CYPXIX
  • P-450AROM

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "Preparation of a novel antiserum to aromatase with high affinity and specificity: Its clinicopathological significance on breast cancer tissue. ". PLoS One. 2017. PMID 28489882.
  • "The effects of Nobiletin, Hesperetin, and Letrozole in a combination on the activity and expression of aromatase in breast cancer cells. ". Cell Mol Biol (Noisy-le-grand). 2017. PMID 28364779.
  • "Acquired CYP19A1 amplification is an early specific mechanism of aromatase inhibitor resistance in ERα metastatic breast cancer. ". Nat Genet. 2017. PMID 28112739.
  • "Aromatase changes in depression: A postmortem and animal experimental study. ". Psychoneuroendocrinology. 2017. PMID 28024269.
  • "Impact of CYP19A1 and ESR1 variants on early-onset side effects during combined endocrine therapy in the TEXT trial.". Breast Cancer Res. 2016. PMID 27825388.

Cyfeiriadau[golygu | golygu cod y dudalen]