CYB5R3

CYB5R3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1UMK
Dynodwyr
Cyfenwau	CYB5R3, B5R, DIA1, cytochrome b5 reductase 3
Dynodwyr allanol	OMIM: 613213 GeneCards: CYB5R3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • flavin adenine dinucleotide binding • ADP binding • NAD binding • FAD binding • cytochrome-b5 reductase activity, acting on NAD(P)H • AMP binding • oxidoreductase activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • endoplasmic reticulum membrane • lipid droplet • mitochondrial outer membrane • hemoglobin complex • mitochondrial inner membrane • extracellular exosome • bilen • mitocondria • Reticwlwm endoplasmig • extracellular region • azurophil granule lumen Prosesau biolegol • steroid metabolic process • sterol biosynthetic process • lipid metabolism • cholesterol metabolic process • blood circulation • cholesterol biosynthetic process • steroid biosynthetic process • L-ascorbic acid metabolic process • xenobiotic metabolic process • neutrophil degranulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1727	n/a
Ensembl	ENSG00000100243	n/a
UniProt	P00387	n/a
RefSeq (mRNA)	NM_007326 NM_000398 NM_001129819 NM_001171660 NM_001171661	n/a
RefSeq (protein)	NP_000389 NP_001123291 NP_001165131 NP_001165132 NP_015565	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CYB5R3 yw CYB5R3 a elwir hefyd yn Cytochrome b5 reductase 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 22, band 22q13.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CYB5R3.

• B5R
• DIA1

Llyfryddiaeth

• "Genetic variation in CYB5R3 is associated with methemoglobin levels in preterm infants receiving nitric oxide therapy. ". Pediatr Res. 2015. PMID 25521918.
• "Clinical spectrum and molecular basis of recessive congenital methemoglobinemia in India. ". Clin Genet. 2015. PMID 24266649.
• "[Population frequency and age of c.806C > T mutation in CYB5R3 gene as cause of recessive congenital methemoglobinemia in Yakutia]. ". Genetika. 2013. PMID 23866629.
• "[Novel large deletion c.22-1320_633+1224del in the CYB5R3 gene from patients with hereditary methemoglobinemia]. ". Genetika. 2012. PMID 23297489.
• "Human cytochrome b5 reductase: structure, function, and potential applications.". Crit Rev Biotechnol. 2014. PMID 23113554.