CXCL5

CXCL5
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2MGS
Dynodwyr
Cyfenwau	CXCL5, ENA-78, SCYB5, C-X-C motif chemokine ligand 5
Dynodwyr allanol	OMIM: 600324 HomoloGene: 88672 GeneCards: CXCL5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • CXCR chemokine receptor binding • cytokine activity • chemokine activity • identical protein binding Cydrannau o'r gell • extracellular region • extracellular space Prosesau biolegol • positive regulation of cell population proliferation • inflammatory response • response to lipopolysaccharide • GO:0072468 signal transduction • cell-cell signaling • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • chemokine-mediated signaling pathway • cell chemotaxis • neutrophil mediated immunity • chemotaxis • defense response • positive regulation of neutrophil chemotaxis • regulation of signaling receptor activity • G protein-coupled receptor signaling pathway • neutrophil chemotaxis • leukocyte chemotaxis • antimicrobial humoral immune response mediated by antimicrobial peptide • cellular response to lipopolysaccharide Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6374	n/a
Ensembl	ENSG00000163735	n/a
UniProt	P42830	n/a
RefSeq (mRNA)	NM_002994	n/a
RefSeq (protein)	NP_002985	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CXCL5 yw CXCL5 a elwir hefyd yn C-X-C motif chemokine ligand 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CXCL5.

• SCYB5
• ENA-78

Llyfryddiaeth

• "Tumor-derived CXCL5 promotes human colorectal cancer metastasis through activation of the ERK/Elk-1/Snail and AKT/GSK3β/β-catenin pathways. ". Mol Cancer. 2017. PMID 28356111.
• "CXCL5 Plays a Promoting Role in Osteosarcoma Cell Migration and Invasion in Autocrine- and Paracrine-Dependent Manners. ". Oncol Res. 2017. PMID 28277189.
• "Neutrophil infiltration mediated by CXCL5 accumulation in the laryngeal squamous cell carcinoma microenvironment: A mechanism by which tumour cells escape immune surveillance. ". Clin Immunol. 2017. PMID 27876461.
• "CXCL5 promotes the proliferation and migration of glioma cells in autocrine- and paracrine-dependent manners. ". Oncol Rep. 2016. PMID 27748886.
• "Molecular Basis of Chemokine CXCL5-Glycosaminoglycan Interactions.". J Biol Chem. 2016. PMID 27471273.