CXCL11

CXCL11
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1RJT
Dynodwyr
Cyfenwau	CXCL11, H174, I-TAC, IP-9, IP9, SCYB11, SCYB9B, b-R1, C-X-C motif chemokine ligand 11
Dynodwyr allanol	OMIM: 604852 HomoloGene: 3944 GeneCards: CXCL11
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • chemokine activity • cytokine activity • heparin binding • GO:0001948, GO:0016582 protein binding • CXCR3 chemokine receptor binding Cydrannau o'r gell • extracellular region • extracellular space • intracellular anatomical structure Prosesau biolegol • chemotaxis • positive regulation of leukocyte chemotaxis • T cell chemotaxis • chemokine-mediated signaling pathway • response to lipopolysaccharide • cell-cell signaling • positive regulation of release of sequestered calcium ion into cytosol • positive regulation of cAMP-mediated signaling • regulation of cell population proliferation • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • GO:0072468 signal transduction • defense response • inflammatory response • antimicrobial humoral immune response mediated by antimicrobial peptide • regulation of signaling receptor activity • G protein-coupled receptor signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • neutrophil chemotaxis • leukocyte chemotaxis • cellular response to lipopolysaccharide Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6373	n/a
Ensembl	ENSG00000169248	n/a
UniProt	O14625	n/a
RefSeq (mRNA)	NM_005409 NM_001302123	n/a
RefSeq (protein)	NP_001289052 NP_005400	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CXCL11 yw CXCL11 a elwir hefyd yn C-X-C motif chemokine ligand 11 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q21.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CXCL11.

• IP9
• H174
• IP-9
• b-R1
• I-TAC
• SCYB11
• SCYB9B

Llyfryddiaeth

• "Hydrogen Peroxide Triggers a Dual Signaling Axis To Selectively Suppress Activated Human T Lymphocyte Migration. ". J Immunol. 2017. PMID 28363904.
• "A variant of the CXCL11 gene may influence susceptibility to contact allergy, particularly in polysensitized patients. ". Contact Dermatitis. 2016. PMID 27356947.
• "Chemokine (C-X-C motif) ligand 11 levels predict survival in cirrhotic patients with transjugular intrahepatic portosystemic shunt. ". Liver Int. 2016. PMID 26212075.
• "CXCL11 in bronchoalveolar lavage fluid and pulmonary function decline in systemic sclerosis. ". Clin Exp Rheumatol. 2012. PMID 22691213.
• "I-TAC is a dominant chemokine in controlling skin intragraft inflammation via recruiting CXCR3+ cells into the graft.". Cell Immunol. 2010. PMID 19875106.