CXCL10

CXCL10
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1O80, 1LV9, 1O7Y, 1O7Z
Dynodwyr
Cyfenwau	CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1, C-X-C motif chemokine ligand 10, C-X-C motif chemokine 10
Dynodwyr allanol	OMIM: 147310 HomoloGene: 1203 GeneCards: CXCL10
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • cytokine activity • heparin binding • CXCR3 chemokine receptor binding • chemokine activity • GO:0001948, GO:0016582 protein binding • cAMP-dependent protein kinase regulator activity • signaling receptor binding • chemoattractant activity Cydrannau o'r gell • extracellular region • external side of plasma membrane • extracellular space • intracellular anatomical structure Prosesau biolegol • regulation of endothelial tube morphogenesis • negative regulation of myoblast differentiation • cellular response to heat • response to vitamin D • positive regulation of cell migration • T cell chemotaxis • chemokine-mediated signaling pathway • cell-cell signaling • response to virus • muscle organ development • positive regulation of monocyte chemotaxis • positive regulation of release of sequestered calcium ion into cytosol • endothelial cell activation • positive regulation of cAMP-mediated signaling • regulation of T cell chemotaxis • blood circulation • chemotaxis • positive regulation of leukocyte chemotaxis • cell surface receptor signaling pathway • response to lipopolysaccharide • negative regulation of myoblast fusion • defense response to virus • regulation of cell population proliferation • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • positive regulation of cell population proliferation • response to auditory stimulus • negative regulation of angiogenesis • response to cold • cellular response to lipopolysaccharide • response to gamma radiation • positive regulation of T cell migration • GO:0072468 signal transduction • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • regulation of protein kinase activity • defense response • inflammatory response • antimicrobial humoral immune response mediated by antimicrobial peptide • regulation of signaling receptor activity • G protein-coupled receptor signaling pathway • cytokine-mediated signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • response to bacterium • neutrophil chemotaxis • leukocyte chemotaxis • positive chemotaxis • regulation of apoptotic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3627	n/a
Ensembl	ENSG00000169245	n/a
UniProt	P02778	n/a
RefSeq (mRNA)	NM_001565	n/a
RefSeq (protein)	NP_001556	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CXCL10 yw CXCL10 a elwir hefyd yn C-X-C motif chemokine ligand 10 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q21.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CXCL10.

• C7
• IFI10
• INP10
• IP-10
• crg-2
• mob-1
• SCYB10
• gIP-10

Llyfryddiaeth

• "Plasma Interferon-Gamma-Inducible Protein 10 Level Associates With Abnormal Memory B Cells Phenotypes in Perinatal HIV Infection. ". Pediatr Infect Dis J. 2017. PMID 28419006.
• "The association of urinary interferon-gamma inducible protein-10 (IP10/CXCL10) levels with kidney allograft rejection. ". Inflamm Res. 2017. PMID 28246678.
• "Blood chemokine profile in untreated early rheumatoid arthritis: CXCL10 as a disease activity marker. ". Arthritis Res Ther. 2017. PMID 28148302.
• "Staphylococcus aureusDownregulates IP-10 Production and Prevents Th1 Cell Recruitment. ". J Immunol. 2017. PMID 28122962.
• "Elevated serum interferon γ-inducible protein-10 in women with polycystic ovary syndrome.". Gynecol Endocrinol. 2017. PMID 28051885.