CUL7

CUL7
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2JNG
Dynodwyr
Cyfenwau	CUL7, 3M1, KIAA0076, dJ20C7.5, cullin 7, CUL-7
Dynodwyr allanol	OMIM: 609577 HomoloGene: 56683 GeneCards: CUL7
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • ubiquitin protein ligase binding Cydrannau o'r gell • cytoplasm • cytosol • centrosome • Golgi apparatus • microtubule organizing center • Cul7-RING ubiquitin ligase complex • perinuclear region of cytoplasm • anaphase-promoting complex • 3M complex • Cytosgerbwd Prosesau biolegol • Golgi organization • ubiquitin-dependent protein catabolic process • placenta development • mitotic cytokinesis • proteolysis • vasculogenesis • IRE1-mediated unfolded protein response • positive regulation of dendrite morphogenesis • protein ubiquitination • epithelial to mesenchymal transition • GO:0022415 viral process • microtubule cytoskeleton organization • regulation of mitotic nuclear division • post-translational protein modification Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9820	n/a
Ensembl	ENSG00000044090	n/a
UniProt	Q14999	n/a
RefSeq (mRNA)	NM_001168370 NM_014780 NM_001374872 NM_001374873 NM_001374874	n/a
RefSeq (protein)	NP_001161842 NP_055595 NP_001361801 NP_001361802 NP_001361803	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CUL7 yw CUL7 a elwir hefyd yn Cullin 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p21.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CUL7.

• 3M1
• CUL-7
• KIAA0076
• dJ20C7.5

Llyfryddiaeth

• "Changes in facial appearance from neonate to adult in 3-M syndrome patient with novel CUL7 gene mutations. ". J Pediatr Endocrinol Metab. 2016. PMID 26488604.
• "Cullin7 is required for lung cancer cell proliferation and is overexpressed in lung cancer. ". Oncol Res. 2015. PMID 25706399.
• "Inhibition of Liver Carcinoma Cell Invasion and Metastasis by Knockdown of Cullin7 In Vitro and In Vivo. ". Oncol Res. 2016. PMID 27053346.
• "High Expression of Cullin7 Correlates with Unfavorable Prognosis in Epithelial Ovarian Cancer Patients. ". Cancer Invest. 2016. PMID 26962950.
• "Pre- and post-natal growth in two sisters with 3-M syndrome.". Eur J Med Genet. 2016. PMID 26850509.