CTTN

CTTN
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1X69, 2D1X
Dynodwyr
Cyfenwau	CTTN, EMS1, cortactin
Dynodwyr allanol	OMIM: 164765 HomoloGene: 3834 GeneCards: CTTN
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• profilin binding; • GO:0001948, GO:0016582 protein binding; • cadherin binding;
Cydrannau o'r gell	• cytoplasm; • Golgi apparatus; • cell projection; • intracellular membrane-bounded organelle; • bilen; • focal adhesion; • growth cone; • ruffle; • voltage-gated potassium channel complex; • cortical cytoskeleton; • Cellbilen; • dendritic spine; • mitotic spindle midzone; • cell junction; • dendrite; • cell cortex; • Microffilament; • podosome; • clathrin-coated pit; • extracellular exosome; • Cytosgerbwd; • lamellipodium; • cytosol;
Prosesau biolegol	• actin cytoskeleton reorganization; • neuron projection morphogenesis; • endocytosis; • positive regulation of actin filament polymerization; • regulation of axon extension; • cell motility; • substrate-dependent cell migration, cell extension; • negative regulation of extrinsic apoptotic signaling pathway; • receptor-mediated endocytosis; • dendritic spine maintenance; • focal adhesion assembly; • actin filament polymerization; • regulation of autophagy of mitochondrion; • lamellipodium organization; • intracellular protein transport; • positive regulation of smooth muscle contraction; • membrane organization;
	Sources:Amigo / QuickGO
Orthologau
	2017
	n/a
	ENSG00000085733; ENSG00000288401
	n/a
	Q14247
	n/a
	NM_001184740; NM_005231; NM_138565
	n/a
	NP_001171669; NP_005222; NP_612632
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CTTN yw CTTN a elwir hefyd yn Cortactin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q13.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CTTN.

EMS1

Llyfryddiaeth

"Cortactin contributes to the tumorigenicity of colorectal cancer by promoting cell proliferation. ". Oncol Rep. 2016. PMID 27805253.
"Cortactin promotes exosome secretion by controlling branched actin dynamics. ". J Cell Biol. 2016. PMID 27402952.
"PI(3,5)P2 controls endosomal branched actin dynamics by regulating cortactin-actin interactions. ". J Cell Biol. 2015. PMID 26323691.
"Expression and clinical significance of cortactin protein in ovarian neoplasms. ". Clin Transl Oncol. 2016. PMID 26243395.
"Expression of cortactin in human gliomas and its effect on migration and invasion of glioma cells.". Oncol Rep. 2015. PMID 26238396.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] CTTN - Cronfa NCBI

[1]

[2]