CTSG

CTSG
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1AU8, 1CGH, 1KYN, 1T32
Dynodwyr
Cyfenwau	CTSG, CATG, CG, cathepsin G
Dynodwyr allanol	OMIM: 116830 HomoloGene: 105646 GeneCards: CTSG
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • heparin binding • GO:0070122 peptidase activity • GO:0001948, GO:0016582 protein binding • hydrolase activity • serine-type endopeptidase activity • serine-type peptidase activity Cydrannau o'r gell • GO:0005578 extracellular matrix • Cellbilen • secretory granule • cell surface • extracellular exosome • cnewyllyn cell • extracellular space • azurophil granule lumen • cytoplasmic stress granule • extracellular region • cytoplasm • collagen-containing extracellular matrix Prosesau biolegol • extracellular matrix disassembly • proteolysis • angiotensin maturation • protein phosphorylation • response to lipopolysaccharide • positive regulation of immune response • defense response to bacterium • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • GO:0051637 defense response to Gram-positive bacterium • antimicrobial humoral response • neutrophil degranulation • defense response to fungus • neutrophil-mediated killing of gram-positive bacterium Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1511	n/a
Ensembl	ENSG00000100448	n/a
UniProt	P08311	n/a
RefSeq (mRNA)	NM_001911	n/a
RefSeq (protein)	NP_001902	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CTSG yw CTSG a elwir hefyd yn Cathepsin G (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 14, band 14q12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CTSG.

• CG
• CATG

Llyfryddiaeth

• "Cell surface cathepsin G activity differs between human natural killer cell subsets. ". Immunol Lett. 2016. PMID 27666013.
• "Lactoferrin Is an Allosteric Enhancer of the Proteolytic Activity of Cathepsin G. ". PLoS One. 2016. PMID 26986619.
• "Cathepsin G-mediated proteolytic degradation of MHC class I molecules to facilitate immune detection of human glioblastoma cells. ". Cancer Immunol Immunother. 2016. PMID 26837514.
• "A novel HLA-A*0201 restricted peptide derived from cathepsin G is an effective immunotherapeutic target in acute myeloid leukemia. ". Clin Cancer Res. 2013. PMID 23147993.
• "AML1-ETO targets and suppresses cathepsin G, a serine protease, which is able to degrade AML1-ETO in t(8;21) acute myeloid leukemia.". Oncogene. 2013. PMID 22641217.