CTSB

CTSB
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3PBH, 1CSB, 1GMY, 1HUC, 1PBH, 2IPP, 2PBH, 3AI8, 3CBJ, 3CBK, 3K9M
Dynodwyr
Cyfenwau	CTSB, APPS, CPSB, cathepsin B, RECEUP
Dynodwyr allanol	OMIM: 116810 HomoloGene: 37550 GeneCards: CTSB
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • cysteine-type peptidase activity • collagen binding • GO:0070122 peptidase activity • GO:0001948, GO:0016582 protein binding • cysteine-type endopeptidase activity • hydrolase activity • proteoglycan binding • serine-type endopeptidase activity • endopeptidase activity Cydrannau o'r gell • intracellular membrane-bounded organelle • melanosome • intracellular anatomical structure • extracellular region • endolysosome lumen • nucleolus • mitocondria • lysosome • extracellular exosome • perinuclear region of cytoplasm • extracellular space • ficolin-1-rich granule lumen • collagen-containing extracellular matrix Prosesau biolegol • regulation of apoptotic process • epithelial cell differentiation • proteolysis • toll-like receptor signaling pathway • decidualization • cellular response to thyroid hormone stimulus • collagen catabolic process • viral entry into host cell • GO:0048552 regulation of catalytic activity • proteolysis involved in cellular protein catabolic process • neutrophil degranulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1508	n/a
Ensembl	ENSG00000164733 ENSG00000285132	n/a
UniProt	P07858	n/a
RefSeq (mRNA)	NM_001908 NM_147780 NM_147781 NM_147782 NM_147783 NM_001317237	n/a
RefSeq (protein)	NP_001304166 NP_001899 NP_680090 NP_680091 NP_680092 NP_680093	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CTSB yw CTSB a elwir hefyd yn Cathepsin B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 8, band 8p23.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CTSB.

• APPS
• CPSB

Llyfryddiaeth

• "Duplicated Enhancer Region Increases Expression of CTSB and Segregates with Keratolytic Winter Erythema in South African and Norwegian Families. ". Am J Hum Genet. 2017. PMID 28457472.
• "Human macrophage cathepsin B-mediated C-terminal cleavage of apolipoprotein A-I at Ser228 severely impairs antiatherogenic capacity. ". FASEB J. 2016. PMID 27630170.
• "Proteomic analysis of silenced cathepsin B expression suggests non-proteolytic cathepsin B functionality. ". Biochim Biophys Acta. 2016. PMID 27526672.
• "Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway. ". J Nutr Biochem. 2016. PMID 27260469.
• "Cathepsin B Expression and the Correlation with Clinical Aspects of Oral Squamous Cell Carcinoma.". PLoS One. 2016. PMID 27031837.