CTPS2

CTPS2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2V4U, 2VKT, 3IHL
Dynodwyr
Cyfenwau	CTPS2, CTP synthase 2, GATD5B
Dynodwyr allanol	OMIM: 300380 HomoloGene: 115908 GeneCards: CTPS2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • ligase activity • nucleotide binding • GO:0001948, GO:0016582 protein binding • ATP binding • CTP synthase activity • identical protein binding Cydrannau o'r gell • cytosol • cytoplasm • cytoophidium Prosesau biolegol • pyrimidine nucleotide metabolic process • glutamine metabolic process • 'de novo' CTP biosynthetic process • pyrimidine nucleotide biosynthetic process • nucleobase-containing small molecule interconversion • CTP biosynthetic process • pyrimidine nucleobase biosynthetic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	56474	n/a
Ensembl	ENSG00000047230	n/a
UniProt	Q9NRF8	n/a
RefSeq (mRNA)	NM_001144002 NM_019857 NM_175859	n/a
RefSeq (protein)	NP_001137474 NP_062831 NP_787055	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CTPS2 yw CTPS2 a elwir hefyd yn CTP synthase 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom X dynol, band Xp22.2.

Llyfryddiaeth

• "Expression of Human CTP synthetase in Saccharomyces cerevisiae reveals phosphorylation by protein kinase A. ". J Biol Chem. 2005. PMID 16179339.
• "Low cytosine triphosphate synthase 2 expression renders resistance to 5-fluorouracil in colorectal cancer. ". Cancer Biol Ther. 2011. PMID 21378502.
• "Comprehensive evaluation of the contribution of X chromosome genes to platinum sensitivity. ". Mol Cancer Ther. 2011. PMID 21252287.
• "Identification of a cDNA encoding an isoform of human CTP synthetase. ". Biochim Biophys Acta. 2000. PMID 10899599.
• "Regulation of human cytidine triphosphate synthetase 2 by phosphorylation.". J Biol Chem. 2010. PMID 20739275.