CTDP1

CTDP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1J2X, 1ONV, 2K7L
Dynodwyr
Cyfenwau	CTDP1, CCFDN, FCP1, CTD phosphatase subunit 1
Dynodwyr allanol	OMIM: 604927 HomoloGene: 31254 GeneCards: CTDP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • RNA polymerase II CTD heptapeptide repeat phosphatase activity • GO:0001948, GO:0016582 protein binding • hydrolase activity • phosphoprotein phosphatase activity • TFIIF-class transcription factor complex binding • Tat protein binding Cydrannau o'r gell • cytoplasm • centrosome • spindle pole • RNA polymerase II, holoenzyme • spindle • microtubule organizing center • midbody • spindle midzone • Cytosgerbwd • cnewyllyn cell • nucleoplasm • intracellular membrane-bounded organelle • GO:0009327 protein-containing complex • actin cytoskeleton • nuclear speck Prosesau biolegol • transcription elongation from RNA polymerase II promoter • GO:0016576 protein dephosphorylation • exit from mitosis • transcription by RNA polymerase II • Cellraniad • negative regulation of cell growth involved in cardiac muscle cell development • dephosphorylation of RNA polymerase II C-terminal domain • cell cycle • positive regulation by host of viral transcription • positive regulation of viral transcription Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9150	n/a
Ensembl	ENSG00000282752 ENSG00000060069	n/a
UniProt	Q9Y5B0	n/a
RefSeq (mRNA)	NM_001202504 NM_004715 NM_048368 NM_001318511	n/a
RefSeq (protein)	NP_001189433 NP_001305440 NP_004706 NP_430255	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CTDP1 yw CTDP1 a elwir hefyd yn RNA polymerase II subunit A C-terminal domain phosphatase a CTD phosphatase subunit 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 18, band 18q23.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CTDP1.

• FCP1
• CCFDN

Llyfryddiaeth

• Congenital Cataracts, Facial Dysmorphism, and Neuropathy. 1993. PMID 20301787.
• "NMR assignment of the intrinsically disordered C-terminal region of Homo sapiens FCP1 in the unbound state. ". Biomol NMR Assign. 2009. PMID 19888685.
• "Identification of Novel Biomarkers for Behcet Disease Diagnosis Using Human Proteome Microarray Approach. ". Mol Cell Proteomics. 2017. PMID 27777341.
• "Lentivirus-mediated knockdown of CTDP1 inhibits lung cancer cell growth in vitro. ". J Cancer Res Clin Oncol. 2016. PMID 26590573.
• "The disordered C-terminus of the RNA polymerase II phosphatase FCP1 is partially helical in the unbound state.". Biochem Biophys Res Commun. 2011. PMID 21672523.