CTBP1

CTBP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1MX3, 4LCE, 4U6Q
Dynodwyr
Cyfenwau	CTBP1, C-terminal binding protein 1, BARS, HADDTS
Dynodwyr allanol	OMIM: 602618 HomoloGene: 1015 GeneCards: CTBP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0050229 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor • GO:0001106 transcription corepressor activity • protein domain specific binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • NAD binding • transcription factor binding • protein C-terminus binding • GO:0001948, GO:0016582 protein binding • oxidoreductase activity • identical protein binding • hydroxypyruvate reductase activity • glyoxylate reductase (NADP+) activity • protein homodimerization activity Cydrannau o'r gell • cytoplasm • transcription regulator complex • transcription repressor complex • nucleoplasm • cnewyllyn cell • cytosol • presynaptic active zone cytoplasmic component • glutamatergic synapse • GABA-ergic synapse Prosesau biolegol • positive regulation of histone deacetylation • cell differentiation • GO:0009373 regulation of transcription, DNA-templated • viral genome replication • GO:1901227 negative regulation of transcription by RNA polymerase II • transcription, DNA-templated • regulation of cell cycle • negative regulation of histone H4 acetylation • protein phosphorylation • white fat cell differentiation • metabolaeth • GO:0022415 viral process • GO:0045996 negative regulation of transcription, DNA-templated • negative regulation of histone acetylation • negative regulation of cell population proliferation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1487	n/a
Ensembl	ENSG00000159692	n/a
UniProt	Q13363	n/a
RefSeq (mRNA)	NM_001012614 NM_001328 NM_001377186 NM_001377187 NM_001377188 NM_001377189 NM_001377190 NM_001377191 NM_001377192 NM_001377193	n/a
RefSeq (protein)	NP_001012632 NP_001319 NP_001364115 NP_001364116 NP_001364117 NP_001364118 NP_001364119 NP_001364120 NP_001364121 NP_001364122	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CTBP1 yw CTBP1 a elwir hefyd yn C-terminal-binding protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4p16.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CTBP1.

• BARS

Llyfryddiaeth

• "Silencing of CtBP1 suppresses the migration in human glioma cells. ". J Mol Histol. 2016. PMID 27160109.
• "CtBP1 associates metabolic syndrome and breast carcinogenesis targeting multiple miRNAs. ". Oncotarget. 2016. PMID 26933806.
• "Prostate tumor growth is impaired by CtBP1 depletion in high-fat diet-fed mice. ". Clin Cancer Res. 2014. PMID 24842953.
• "Nicotinamide adenine dinucleotide-induced multimerization of the co-repressor CtBP1 relies on a switching tryptophan. ". J Biol Chem. 2013. PMID 23940047.
• "CtBP1 is involved in epithelial-mesenchymal transition and is a potential therapeutic target for hepatocellular carcinoma.". Oncol Rep. 2013. PMID 23756565.