CSTB

CSTB
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1STF, 2OCT, 4N6V
Dynodwyr
Cyfenwau	CSTB, CST6, EPM1, EPM1A, PME, STFB, ULD, Cystatin B, CPI-B
Dynodwyr allanol	OMIM: 601145 HomoloGene: 79 GeneCards: CSTB
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • peptidase inhibitor activity • protease binding • endopeptidase inhibitor activity • cysteine-type endopeptidase inhibitor activity • RNA binding Cydrannau o'r gell • cytoplasm • nucleolus • extracellular exosome • intracellular anatomical structure • cnewyllyn cell • extracellular region • extracellular space • cytosol • secretory granule lumen • tertiary granule lumen • ficolin-1-rich granule lumen • collagen-containing extracellular matrix Prosesau biolegol • adult locomotory behavior • negative regulation of proteolysis • negative regulation of peptidase activity • negative regulation of endopeptidase activity • neutrophil degranulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1476	n/a
Ensembl	ENSG00000160213	n/a
UniProt	P04080	n/a
RefSeq (mRNA)	NM_000100	n/a
RefSeq (protein)	NP_000091	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CSTB yw CSTB a elwir hefyd yn Cystatin B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 21, band 21q22.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CSTB.

• PME
• ULD
• CST6
• EPM1
• STFB
• CPI-B
• EPM1A

Llyfryddiaeth

• "Severe neurodegeneration, progressive cerebral volume loss and diffuse hypomyelination associated with a homozygous frameshift mutation in CSTB. ". Eur J Hum Genet. 2017. PMID 28378817.
• "CSTB Downregulation Promotes Cell Proliferation and Migration and Suppresses Apoptosis in Gastric Cancer SGC-7901 Cell Line. ". Oncol Res. 2016. PMID 28281969.
• "Cystatin B and HIV regulate the STAT-1 signaling circuit in HIV-infected and INF-β-treated human macrophages. ". J Neurovirol. 2016. PMID 27137788.
• "CSTB null mutation associated with microcephaly, early developmental delay, and severe dyskinesia. ". Neurology. 2016. PMID 26843564.
• "Refining the phenotype of Unverricht-Lundborg disease (EPM1): a population-wide Finnish study.". Neurology. 2015. PMID 25770194.