CSTA

CSTA
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1CYU, 1CYV, 1DVC, 1DVD, 1GD3, 1GD4, 1N9J, 1NB3, 1NB5, 3K9M, 3KFQ, 3KSE
Dynodwyr
Cyfenwau	CSTA, AREI, STF1, STFA, Cystatin A, PSS4
Dynodwyr allanol	OMIM: 184600 HomoloGene: 3819 GeneCards: CSTA
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • peptidase inhibitor activity • protease binding • protein-macromolecule adaptor activity • endopeptidase inhibitor activity • structural molecule activity • cysteine-type endopeptidase inhibitor activity Cydrannau o'r gell • cytoplasm • intracellular anatomical structure • cornified envelope • extracellular space • cnewyllyn cell • cytosol Prosesau biolegol • negative regulation of proteolysis • GO:0051357, GO:0051358, GO:0051359 peptide cross-linking • negative regulation of peptidase activity • cell adhesion • keratinocyte differentiation • negative regulation of endopeptidase activity • cornification • cell-cell adhesion Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1475	n/a
Ensembl	ENSG00000121552	n/a
UniProt	P01040	n/a
RefSeq (mRNA)	NM_005213	n/a
RefSeq (protein)	NP_005204	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CSTA yw CSTA a elwir hefyd yn Cystatin A (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3q21.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CSTA.

• AREI
• PSS4
• STF1
• STFA

Llyfryddiaeth

• "Myoepithelial cell-specific expression of stefin A as a suppressor of early breast cancer invasion. ". J Pathol. 2017. PMID 29086922.
• "Acral peeling skin syndrome resulting from a homozygous nonsense mutation in the CSTA gene encoding cystatin A. ". Pediatr Dermatol. 2013. PMID 23534700.
• "Modulation of cystatin A expression in human airway epithelium related to genotype, smoking, COPD, and lung cancer. ". Cancer Res. 2011. PMID 21325429.
• "Identification of candidate nasopharyngeal carcinoma serum biomarkers by cancer cell secretome and tissue transcriptome analysis: potential usage of cystatin A for predicting nodal stage and poor prognosis. ". Proteomics. 2010. PMID 20461718.
• "Modulation of allergenicity of major house dust mite allergens Der f 1 and Der p 1 by interaction with an endogenous ligand.". J Immunol. 2009. PMID 19933866.