CST7

CST7
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2CH9
Dynodwyr
Cyfenwau	CST7, CMAP, cystatin F
Dynodwyr allanol	OMIM: 603253 HomoloGene: 37832 GeneCards: CST7
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • peptidase inhibitor activity • endopeptidase inhibitor activity • GO:0001948, GO:0016582 protein binding • protease binding • cysteine-type endopeptidase inhibitor activity • protein homodimerization activity Cydrannau o'r gell • cytoplasm • extracellular region • extracellular space • lysosome • endosome • late endosome • multivesicular body • Reticwlwm endoplasmig • Golgi apparatus • GO:0016023 cytoplasmic vesicle Prosesau biolegol • negative regulation of peptidase activity • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • negative regulation of cysteine-type endopeptidase activity • negative regulation of endopeptidase activity • positive regulation of myelination • inhibition of cysteine-type endopeptidase activity • negative regulation of microglial cell activation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8530	n/a
Ensembl	ENSG00000077984	n/a
UniProt	O76096	n/a
RefSeq (mRNA)	NM_003650	n/a
RefSeq (protein)	NP_003641	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CST7 yw CST7 a elwir hefyd yn Cystatin F (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 20, band 20p11.21.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CST7.

• CMAP

Llyfryddiaeth

• "Cystatin F is secreted, but artificial modification of its C-terminus can induce its endocytic targeting. ". Exp Cell Res. 2004. PMID 15212960.
• "Regulated expression and intracellular localization of cystatin F in human U937 cells. ". Eur J Biochem. 2002. PMID 12423348.
• "Glycosylation directs targeting and activation of cystatin f from intracellular and extracellular sources. ". Traffic. 2009. PMID 19192250.
• "Structural basis of reduction-dependent activation of human cystatin F. ". J Biol Chem. 2006. PMID 16601115.
• "Inhibitory properties of cystatin F and its localization in U937 promonocyte cells.". FEBS J. 2005. PMID 15752368.