CSRP3

CSRP3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2O10, 2O13
Dynodwyr
Cyfenwau	CSRP3, CLP, CMD1M, CMH12, CRP3, LMO4, MLP, cysteine and glycine rich protein 3
Dynodwyr allanol	OMIM: 600824 HomoloGene: 20742 GeneCards: CSRP3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • actinin binding • metal ion binding • telethonin binding • GO:0001948, GO:0016582 protein binding • structural constituent of muscle • actin binding • identical protein binding Cydrannau o'r gell • cytoplasm • Z discdkac • Cytosgerbwd • cnewyllyn cell • sarcomere Prosesau biolegol • protein localization to organelle • cell differentiation • negative regulation of myoblast differentiation • cardiac muscle contraction • cardiac muscle tissue development • regulation of the force of heart contraction • cardiac muscle hypertrophy • muscle organ development • cellular calcium ion homeostasis • positive regulation of actin filament severing • detection of muscle stretch • cardiac myofibril assembly • multicellular organism development • positive regulation of myoblast differentiation • negative regulation of actin filament severing • skeletal muscle tissue development • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • transcription, DNA-templated • GO:0009373 regulation of transcription, DNA-templated • inflammatory response • heart development • GO:1901047 insulin receptor signaling pathway • T-tubule organization • glucose homeostasis • protein kinase C signaling • regulation of protein localization to plasma membrane • actin cytoskeleton organization • sarcomere organization • muscle tissue development Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8048	n/a
Ensembl	ENSG00000129170	n/a
UniProt	P50461	n/a
RefSeq (mRNA)	NM_003476 NM_001369404	n/a
RefSeq (protein)	NP_003467	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CSRP3 yw CSRP3 a elwir hefyd yn Cysteine and glycine rich protein 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11p15.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CSRP3.

• CLP
• MLP
• CRP3
• LMO4
• CMD1M
• CMH12

Llyfryddiaeth

• "Beyond the sarcomere: CSRP3 mutations cause hypertrophic cardiomyopathy. ". Hum Mol Genet. 2008. PMID 18505755.
• "Human heart LIM protein has transcription activation ability related to LIM domain 1. ". Biochemistry (Mosc). 2008. PMID 18393774.
• "Human muscle LIM protein dimerizes along the actin cytoskeleton and cross-links actin filaments. ". Mol Cell Biol. 2014. PMID 24934443.
• "1H, 13C, and 15N assignment of the muscular LIM protein MLP/CRP3. ". Biomol NMR Assign. 2007. PMID 19636821.
• "Structure and dynamics of the human muscle LIM protein.". FEBS Lett. 2009. PMID 19230835.