CSNK1E

CSNK1E
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4HNI, 4HOK
Dynodwyr
Cyfenwau	CSNK1E, CKIepsilon, HCKIE, Casein kinase 1 isoform epsilon, casein kinase 1 epsilon, CKIe
Dynodwyr allanol	OMIM: 600863 HomoloGene: 121695 GeneCards: CSNK1E
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • protein kinase activity • nucleotide binding • kinase activity • protein serine/threonine kinase activity • GO:0001948, GO:0016582 protein binding • ATP binding • RNA binding Cydrannau o'r gell • cytoplasm • cytosol • cnewyllyn cell • nucleoplasm • growth cone • neuron projection • neuronal cell body Prosesau biolegol • phosphorylation • proses rythmig • Wnt signaling pathway • negative regulation of protein binding • protein phosphorylation • G2/M transition of mitotic cell cycle • GO:0035404 peptidyl-serine phosphorylation • GO:0100026 DNA repair • GO:0072468 signal transduction • endocytosis • regulation of cell shape • rRNA processing • ciliary basal body-plasma membrane docking • positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation • positive regulation of proteasomal ubiquitin-dependent protein catabolic process • circadian regulation of gene expression • regulation of circadian rhythm • positive regulation of non-canonical Wnt signaling pathway • regulation of G2/M transition of mitotic cell cycle • circadian behavior • positive regulation of amyloid-beta formation • cellular response to nerve growth factor stimulus • peptidyl-threonine phosphorylation • canonical Wnt signaling pathway • positive regulation of canonical Wnt signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1454	n/a
Ensembl	ENSG00000213923	n/a
UniProt	P49674	n/a
RefSeq (mRNA)	NM_001894 NM_152221	n/a
RefSeq (protein)	NP_001885 NP_689407	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CSNK1E yw CSNK1E a elwir hefyd yn Casein kinase 1 epsilon (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 22, band 22q13.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CSNK1E.

• HCKIE
• CKIepsilon

Llyfryddiaeth

• "Low cytoplasmic casein kinase 1 epsilon expression predicts poor prognosis in patients with hepatocellular carcinoma. ". Tumour Biol. 2016. PMID 26482619.
• "High casein kinase 1 epsilon levels are correlated with better prognosis in subsets of patients with breast cancer. ". Oncotarget. 2015. PMID 26327509.
• "KNOCKDOWN OF CASEIN KINASE 1e INHIBITS CELL PROLIFERATION AND INVASION OF COLORECTAL CANCER CELLS VIA INHIBITION OF THE Wnt/β-CATENIN SIGNALING. ". J Biol Regul Homeost Agents. 2015. PMID 26122218.
• "Dopaminergic pathway polymorphisms and heroin addiction: further support for association of CSNK1E variants. ". Pharmacogenomics. 2014. PMID 25521358.
• "Casein kinase 1 epsilon expression predicts poorer prognosis in low T-stage oral cancer patients.". Int J Mol Sci. 2014. PMID 24557581.