CSF3

CSF3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2D9Q, 1CD9, 1GNC, 1PGR, 1RHG
Dynodwyr
Cyfenwau	CSF3, C17orf33, CSF3OS, GCSF, colony stimulating factor 3
Dynodwyr allanol	OMIM: 138970 HomoloGene: 7677 GeneCards: CSF3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • cytokine activity • enzyme binding • growth factor activity • granulocyte colony-stimulating factor receptor binding Cydrannau o'r gell • extracellular region • extracellular space Prosesau biolegol • positive regulation of protein kinase B signaling • positive regulation of actin filament polymerization • cellular response to cytokine stimulus • positive regulation of peptidyl-serine phosphorylation • multicellular organism development • granulocyte differentiation • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • positive regulation of peptidyl-tyrosine phosphorylation • positive regulation of phosphatidylinositol 3-kinase signaling • positive regulation of protein binding • cellular response to lipopolysaccharide • positive regulation of actin cytoskeleton reorganization • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • negative regulation of neuron death • positive regulation of myeloid cell differentiation • response to ethanol • positive regulation of cell population proliferation • neutrophil differentiation • macrophage differentiation • myeloid cell development • regulation of signaling receptor activity • cytokine-mediated signaling pathway • positive regulation of DNA-binding transcription factor activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1440	n/a
Ensembl	ENSG00000108342	n/a
UniProt	P09919	n/a
RefSeq (mRNA)	NM_000759 NM_001178147 NM_172219 NM_172220	n/a
RefSeq (protein)	NP_000750 NP_001171618 NP_757373 NP_757374	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CSF3 yw CSF3 a elwir hefyd yn Colony stimulating factor 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17q21.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CSF3.

• GCSF
• CSF3OS
• C17orf33

Llyfryddiaeth

• "Granulocyte colony-stimulating factor decreases the Th1/Th2 ratio in peripheral blood mononuclear cells from patients with chronic immune thrombocytopenic purpura in vitro. ". Thromb Res. 2016. PMID 27815970.
• "Keratinocyte-Releasable Factors Stimulate the Expression of Granulocyte Colony-Stimulating Factor in Human Dermal Fibroblasts. ". J Cell Biochem. 2017. PMID 27340768.
• "Effect of Granulocyte-Colony Stimulating Factor on Endothelial Cells and Osteoblasts. ". Biomed Res Int. 2016. PMID 27006951.
• "Granulocyte colony-stimulating factor impairs CD8(+) T cell functionality by interfering with central activation elements. ". Clin Exp Immunol. 2016. PMID 26990855.
• "The significance of G-CSF expression and myeloid-derived suppressor cells in the chemoresistance of uterine cervical cancer.". Sci Rep. 2015. PMID 26666576.