CRYM

CRYM
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2I99
Dynodwyr
Cyfenwau	CRYM, DFNA40, THBP, crystallin mu
Dynodwyr allanol	OMIM: 123740 HomoloGene: 1424 GeneCards: CRYM
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • oxidoreductase activity • hormone binding • GO:0001948, GO:0016582 protein binding • protein homodimerization activity • GO:0001106 transcription corepressor activity • NADP binding • thyroid hormone binding • thiomorpholine-carboxylate dehydrogenase activity • oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor Cydrannau o'r gell • cytoplasm • extracellular exosome • mitocondria • cnewyllyn cell • peroxisomal matrix • cytosol Prosesau biolegol • thyroid hormone transport • GO:1901227 negative regulation of transcription by RNA polymerase II • sensory perception of sound • lysine catabolic process • thyroid hormone metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1428	n/a
Ensembl	ENSG00000103316	n/a
UniProt	Q14894	n/a
RefSeq (mRNA)	NM_001014444 NM_001888 NM_001376256	n/a
RefSeq (protein)	NP_001879 NP_001363185	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CRYM yw CRYM a elwir hefyd yn Ketimine reductase mu-crystallin a Crystallin mu (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 16, band 16p12.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CRYM.

• THBP
• DFNA40

Llyfryddiaeth

• "Ketimine reductase/CRYM catalyzes reductive alkylamination of α-keto acids, confirming its function as an imine reductase. ". Amino Acids. 2015. PMID 26173510.
• "Insights into Enzyme Catalysis and Thyroid Hormone Regulation of Cerebral Ketimine Reductase/μ-Crystallin Under Physiological Conditions. ". Neurochem Res. 2015. PMID 25931162.
• "Adipose tissue μ-crystallin is a thyroid hormone-binding protein associated with systemic insulin sensitivity. ". J Clin Endocrinol Metab. 2014. PMID 25057873.
• "Crystallin-gazing: unveiling enzymatic activity. ". J Neurochem. 2011. PMID 21418222.
• "Mammalian forebrain ketimine reductase identified as μ-crystallin; potential regulation by thyroid hormones.". J Neurochem. 2011. PMID 21332720.