CRMP1

CRMP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4B3Z
Dynodwyr
Cyfenwau	CRMP1, CRMP-1, DPYSL1, DRP-1, DRP1, ULIP-3, collapsin response mediator protein 1
Dynodwyr allanol	OMIM: 602462 HomoloGene: 20347 GeneCards: CRMP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • hydrolase activity • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds • filamin binding Cydrannau o'r gell • spindle • Cytosgerbwd • microtubule organizing center • cytoplasm • cytosol • midbody • centrosome • cnewyllyn cell Prosesau biolegol • neuron development • nucleobase-containing compound metabolic process • microtubule cytoskeleton organization • nervous system development • axon guidance • negative regulation of actin filament binding • negative regulation of neuron projection development Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1400	n/a
Ensembl	ENSG00000072832	n/a
UniProt	Q14194	n/a
RefSeq (mRNA)	NM_001313 NM_001014809 NM_001288661 NM_001288662	n/a
RefSeq (protein)	NP_001014809 NP_001275590 NP_001275591 NP_001304	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CRMP1 yw CRMP1 a elwir hefyd yn Collapsin response mediator protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4p16.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CRMP1.

• DRP1
• DRP-1
• CRMP-1
• DPYSL1
• ULIP-3

Llyfryddiaeth

• "Collapsin response mediator protein-1 (CRMP1) acts as an invasion and metastasis suppressor of prostate cancer via its suppression of epithelial-mesenchymal transition and remodeling of actin cytoskeleton organization. ". Oncogene. 2017. PMID 27321179.
• "Structure of human collapsin response mediator protein 1: a possible role of its C-terminal tail. ". Acta Crystallogr F Struct Biol Commun. 2015. PMID 26249678.
• "Expression of collapsin response mediator protein 1 in placenta of normal gestation and link to early-onset preeclampsia. ". Reprod Sci. 2015. PMID 25194153.
• "Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits. ". Hum Mol Genet. 2012. PMID 22798627.
• "Down-regulation of CRMP-1 in patients with epilepsy and a rat model.". Neurochem Res. 2012. PMID 22359051.