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CRKL

Oddi ar Wicipedia
CRKL
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauCRKL, CRK like proto-oncogene, adaptor protein
Dynodwyr allanolOMIM: 602007 HomoloGene: 38021 GeneCards: CRKL
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005207

n/a

RefSeq (protein)

NP_005198

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CRKL yw CRKL a elwir hefyd yn CRK like proto-oncogene, adaptor protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 22, band 22q11.21.[2]

Llyfryddiaeth

[golygu | golygu cod]
  • "Reduction of CRKL expression in patients with partial DiGeorge syndrome is associated with impairment of T-cell functions. ". J Allergy Clin Immunol. 2016. PMID 26875746.
  • "CrkL meditates CCL20/CCR6-induced EMT in gastric cancer. ". Cytokine. 2015. PMID 26044596.
  • "The role of CT10 regulation of kinase-like in cancer. ". Future Oncol. 2014. PMID 25531052.
  • "CrkL regulates SDF-1-induced breast cancer biology through balancing Erk1/2 and PI3K/Akt pathways. ". Med Oncol. 2015. PMID 25476480.
  • "CRKL protein overexpression enhances cell proliferation and invasion in pancreatic cancer.". Tumour Biol. 2015. PMID 25318601.

Cyfeiriadau

[golygu | golygu cod]
  1. "Human PubMed Reference:".
  2. CRKL - Cronfa NCBI