CRABP2

CRABP2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1BLR, 1BM5, 1CBQ, 1CBS, 1XCA, 2CBS, 2FR3, 2FRS, 2FS6, 2FS7, 2G78, 2G79, 2G7B, 3CBS, 3CR6, 3CWK, 3D95, 3D96, 3D97, 3F8A, 3F9D, 3FA6, 3FA7, 3FA8, 3FA9, 3FEK, 3FEL, 3FEN, 3FEP, 3I17, 4I9R, 4I9S, 4M6S, 4M7M, 4QGV, 4QGW, 4QGX, 4YBP, 4YBU, 4YKM, 4YKO, 4YCH, 4YGZ, 4YFP, 4YFQ, 4YGH, 4YH0, 4YFR, 4YCE, 4YGG, 4YDA, 4YDB, 5HZQ
Dynodwyr
Cyfenwau	CRABP2, CRABP-II, RBP6, cellular retinoic acid binding protein 2
Dynodwyr allanol	OMIM: 180231 HomoloGene: 1415 GeneCards: CRABP2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transporter activity • lipid binding • retinol binding • retinoic acid binding • GO:0001948, GO:0016582 protein binding • retinal binding • retinoid binding Cydrannau o'r gell • extracellular exosome • Reticwlwm endoplasmig • cnewyllyn cell • nucleoplasm • cytoplasm • cytosol Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • positive regulation of collateral sprouting • retinoic acid metabolic process • embryonic forelimb morphogenesis • GO:0072468 signal transduction • regulation of retinoic acid receptor signaling pathway • epidermis development • retinoic acid biosynthetic process • GO:0015915 transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1382	n/a
Ensembl	ENSG00000143320	n/a
UniProt	P29373	n/a
RefSeq (mRNA)	NM_001878 NM_001199723	n/a
RefSeq (protein)	NP_001186652 NP_001869	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CRABP2 yw CRABP2 a elwir hefyd yn Cellular retinoic acid binding protein 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q23.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CRABP2.

• RBP6
• CRABP-II

Llyfryddiaeth

• "The Cellular Retinoic Acid Binding Protein 2 Promotes Survival of Malignant Peripheral Nerve Sheath Tumor Cells. ". Am J Pathol. 2017. PMID 28502478.
• "Association between cytoplasmic CRABP2, altered retinoic acid signaling, and poor prognosis in glioblastoma. ". Glia. 2016. PMID 26893190.
• "Cellular Retinoic Acid Binding Protein 2 Is Strikingly Downregulated in Human Esophageal Squamous Cell Carcinoma and Functions as a Tumor Suppressor. ". PLoS One. 2016. PMID 26839961.
• "CRABP-II is a highly sensitive and specific diagnostic molecular marker for pancreatic ductal adenocarcinoma in distinguishing from benign pancreatic conditions. ". Hum Pathol. 2014. PMID 24709110.
• "Rational design of a colorimetric pH sensor from a soluble retinoic acid chaperone.". J Am Chem Soc. 2013. PMID 24059243.