CRABP1

CRABP1
Dynodwyr
Cyfenwau	CRABP1, CRABP, CRABP-I, CRABPI, RBP5, cellular retinoic acid binding protein 1
Dynodwyr allanol	OMIM: 180230 HomoloGene: 3222 GeneCards: CRABP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • retinol binding • retinoic acid binding • GO:0001948, GO:0016582 protein binding • retinoid binding • retinal binding • lipid binding Cydrannau o'r gell • cytoplasm • cytosol Prosesau biolegol • multicellular organism development • retinoic acid catabolic process • GO:0072468 signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1381	n/a
Ensembl	ENSG00000166426	n/a
UniProt	P29762	n/a
RefSeq (mRNA)	NM_004378	n/a
RefSeq (protein)	NP_004369	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CRABP1 yw CRABP1 a elwir hefyd yn Cellular retinoic acid-binding protein 1 a Cellular retinoic acid binding protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 15, band 15q25.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CRABP1.

• RBP5
• CRABP
• CRABPI
• CRABP-I

Llyfryddiaeth

• "CRABP1 is associated with a poor prognosis in breast cancer: adding to the complexity of breast cancer cell response to retinoic acid. ". Mol Cancer. 2015. PMID 26142905.
• "CRABP1 provides high malignancy of transformed mesenchymal cells and contributes to the pathogenesis of mesenchymal and neuroendocrine tumors. ". Cell Cycle. 2014. PMID 24626200.
• "CRABP1-reduced expression is associated with poorer prognosis in serous and clear cell ovarian adenocarcinoma. ". J Cancer Res Clin Oncol. 2011. PMID 20571827.
• "Upregulation of CRABP1 in human neuroblastoma cells overproducing the Alzheimer-typical Abeta42 reduces their differentiation potential. ". BMC Med. 2008. PMID 19087254.
• "Overexpression of CRABPI in suprabasal keratinocytes enhances the proliferation of epidermal basal keratinocytes in mouse skin topically treated with all-trans retinoic acid.". Exp Cell Res. 2008. PMID 17727842.