CR2

CR2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1GHQ, 1LY2, 1W2R, 1W2S, 2GSX, 3OED
Dynodwyr
Cyfenwau	CR2, C3DR, CD21, CR, CVID7, SLEB9, complement component 3d receptor 2, complement C3d receptor 2
Dynodwyr allanol	OMIM: 120650 HomoloGene: 55611 GeneCards: CR2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • protein homodimerization activity • virus receptor activity • complement binding • transmembrane signaling receptor activity • complement receptor activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • integral component of membrane • bilen • receptor complex • extracellular exosome • Cellbilen Prosesau biolegol • immune system process • B cell proliferation • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • complement activation, classical pathway • viral entry into host cell • B cell differentiation • innate immune response • GO:0022415 viral process • complement receptor mediated signaling pathway • GO:0072468 signal transduction • regulation of complement activation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1380	n/a
Ensembl	ENSG00000117322	n/a
UniProt	P20023	n/a
RefSeq (mRNA)	NM_001006658 NM_001877	n/a
RefSeq (protein)	NP_001006659 NP_001868	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CR2 yw CR2 a elwir hefyd yn Complement C3d receptor 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q32.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CR2.

• CR
• C3DR
• CD21
• CVID7
• SLEB9

Llyfryddiaeth

• "Reversion of anergy signatures in clonal CD21low B cells of mixed cryoglobulinemia after clearance of HCV viremia. ". Blood. 2017. PMID 28507081.
• "Association of Complement Receptor 2 Gene Polymorphisms with Susceptibility to Osteonecrosis of the Femoral Head in Systemic Lupus Erythematosus. ". Biomed Res Int. 2016. PMID 27446959.
• "The antigenic complex in HIT binds to B cells via complement and complement receptor 2 (CD21). ". Blood. 2016. PMID 27412887.
• "5'UTR +24T>C CR2 is not associated with nasopharyngeal carcinoma development in the North Region of Portugal. ". Oral Dis. 2016. PMID 26748973.
• "A CD21 low phenotype, with no evidence of autoantibodies to complement proteins, is consistent with a poor prognosis in CLL.". Oncotarget. 2015. PMID 26452134.