CPM

CPM
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1UWY
Dynodwyr
Cyfenwau	CPM, carboxypeptidase M
Dynodwyr allanol	OMIM: 114860 HomoloGene: 35367 GeneCards: CPM
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • carboxypeptidase activity • GO:0070122 peptidase activity • zinc ion binding • hydrolase activity • metallopeptidase activity • metal ion binding • metallocarboxypeptidase activity • serine-type carboxypeptidase activity Cydrannau o'r gell • anchored component of membrane • cell surface • Cellbilen • extracellular exosome • bilen • extracellular region • extracellular space Prosesau biolegol • protein processing • anatomical structure morphogenesis • proteolysis • peptide metabolic process • C-terminal protein lipidation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1368	n/a
Ensembl	ENSG00000135678	n/a
UniProt	P14384	n/a
RefSeq (mRNA)	NM_001005502 NM_001874 NM_198320	n/a
RefSeq (protein)	NP_001005502 NP_001865 NP_938079	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CPM yw CPM a elwir hefyd yn Carboxypeptidase M (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q15.

Llyfryddiaeth

• "Mapping of carboxypeptidase m in normal human kidney and renal cell carcinoma: expression in tumor-associated neovasculature and macrophages. ". J Histochem Cytochem. 2013. PMID 23172796.
• "Carboxypeptidase-M is regulated by lipids and CSFs in macrophages and dendritic cells and expressed selectively in tissue granulomas and foam cells. ". Lab Invest. 2012. PMID 22157720.
• "Carboxypeptidase M: a biomarker for the discrimination of well-differentiated liposarcoma from lipoma. ". Mod Pathol. 2009. PMID 19820690.
• "Crystal structure of human carboxypeptidase M, a membrane-bound enzyme that regulates peptide hormone activity. ". J Mol Biol. 2004. PMID 15066430.
• "Effect of mutation of two critical glutamic acid residues on the activity and stability of human carboxypeptidase M and characterization of its signal for glycosylphosphatidylinositol anchoring.". Biochem J. 2003. PMID 12457462.