CPA4

CPA4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2BO9, 2BOA, 2PCU, 4A94, 4BD9
Dynodwyr
Cyfenwau	CPA4, CPA3, carboxypeptidase A4
Dynodwyr allanol	OMIM: 607635 HomoloGene: 56753 GeneCards: CPA4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • carboxypeptidase activity • GO:0070122 peptidase activity • zinc ion binding • hydrolase activity • metallopeptidase activity • metal ion binding • metallocarboxypeptidase activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • extracellular region • extracellular space • cydran cellog Prosesau biolegol • histone acetylation • proteolysis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	51200	n/a
Ensembl	n/a	n/a
UniProt	Q9UI42	n/a
RefSeq (mRNA)	NM_016352 NM_001163446	n/a
RefSeq (protein)	NP_001156918 NP_057436	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CPA4 yw CPA4 a elwir hefyd yn Carboxypeptidase A4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7q32.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CPA4.

• CPA3

Llyfryddiaeth

• "Detailed molecular comparison between the inhibition mode of A/B-type carboxypeptidases in the zymogen state and by the endogenous inhibitor latexin. ". Cell Mol Life Sci. 2005. PMID 16091843.
• "Characterization of the substrate specificity of human carboxypeptidase A4 and implications for a role in extracellular peptide processing. ". J Biol Chem. 2010. PMID 20385563.
• "A noncanonical mechanism of carboxypeptidase inhibition revealed by the crystal structure of the Tri-Kunitz SmCI in complex with human CPA4. ". Structure. 2013. PMID 23746805.
• "Crystal structure of novel metallocarboxypeptidase inhibitor from marine mollusk Nerita versicolor in complex with human carboxypeptidase A4. ". J Biol Chem. 2012. PMID 22294694.
• "Carboxypeptidase 4 gene variants and early-onset intermediate-to-high risk prostate cancer.". BMC Cancer. 2009. PMID 19245716.